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Healthy Volunteers Clinical Trials near Durham, NC

172 studies for Healthy Volunteers are recruiting at 202 sites within 50 miles of Durham, North Carolina, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Healthy Volunteers trials in the US or all trials near Durham.

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Healthy Volunteers studies enrolling near Durham

Showing the 50 nearest of 172 studies.
  1. A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

    NCT07282665

    • Phase 3
    • Ages 65 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Duke Vaccine and Trials Unit (Durham, NC); Accellacare - Cary (Cary, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  2. Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

    NCT04262206

    • Phase 4
    • Ages 75 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Duke University (Durham, NC); PREVENTABLE Tele-Site (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  3. A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

    NCT06112418

    • Interventional
    • Ages 55 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Duke University Hospital (Durham, NC); Durham Veterans Affairs Medical Center (Durham VAMC) (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  4. BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

    NCT07160244

    • Phase 3
    • Ages 1 day to 49 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Duke University - Main Hospital and Clinics (Durham, NC); Duke University - Main Hospital and Clinics (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  5. Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

    NCT01574053

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Duke University (Durham, NC); Virginia Commonwealth University Parkinson's and Movement Disorders Center (Henrico, VA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  6. Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

    NCT05237258

    • Interventional
    • Ages 18 to 120 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Duke University (Durham, NC); University of North Carolina at Chapel Hill (Chapel Hill, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  7. Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

    NCT06071377

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Duke University (Durham, NC); University of North Carolina (Chapel Hill, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  8. Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial

    NCT06605118

    • Phase 3
    • Ages Any age
    • Sex: Female
    • Accepts healthy volunteers

    Nearest sites: Duke University (Durham, NC); University of North Carolina - Chapel Hill (Chapel Hill, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  9. A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose

    NCT06866405

    • Phase 3
    • Ages 0 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Duke University - Main Hospital and Clinics (Durham, NC); Duke University - Main Hospital and Clinics (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  10. Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

    NCT06980025

    • Phase 3
    • Ages 14 years and older
    • Sex: Female
    • Accepts healthy volunteers

    Nearest sites: Duke University (Durham, NC); University of North Carolina - Chapel Hill (Chapel Hill, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  11. The Vanguard Study: Testing a New Way to Screen for Cancer

    NCT06995898

    • Interventional
    • Ages 45 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Durham VA Medical Center (Durham, NC); UNC Lineberger Comprehensive Cancer Center (Chapel Hill, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  12. IAP-086-1: A Phase 1 Single Ascending Dose First-Time in Human Study

    NCT07596888

    • Phase 1
    • Ages 18 to 70 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Duke Early Phase Clinical Research Unit (Durham, NC); University of North Carolina (Chapel Hill, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  13. A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.

    NCT07629440

    • Phase 3
    • Ages 42 to 211 days
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Duke Vaccine and Trials Unit (Durham, NC); Durham Pediatrics at North Duke Street (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  14. A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

    NCT07805707

    • Phase 3
    • Ages 65 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: GSK Investigational Site (Durham, NC); GSK Investigational Site (Raleigh, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  15. Genetic and Environmental Risk Factors for Hemorrhagic Stroke

    NCT00682695

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. Cervical Cancer Detection Using Optical Spectroscopy

    NCT00900575

    • Interventional
    • Ages 18 years and older
    • Sex: Female
    • Accepts healthy volunteers

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. Hyperpolarized 129Xe MRI for Imaging Pulmonary Function

    NCT01280994

    • Phase 2
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. SC2i Tissue and Data Repository Protocol

    NCT02182180

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Health Systems (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

    NCT02450851

    • Observational
    • Ages 1 month to 100 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Health System (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. Retinal Imaging in Neurodegenerative Disease

    NCT03233646

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. Maternal Autoimmune Disease Research Alliance (MADRA) Registry

    NCT03276923

    • Observational
    • Ages Any age
    • Sex: Female
    • Accepts healthy volunteers

    Nearest site: Duke University (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. Intraoperative OCT Guidance of Intraocular Surgery II

    NCT03713268

    • Observational
    • Ages 4 weeks and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Eye Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. Observational Pharmaco-Epidemiology Research & Analysis

    NCT03813862

    • Observational
    • Ages 0 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Epividian (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. Supplementing L-citrulline to Overweight Late Asthma oNset Phenotypes

    NCT03885245

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University (Asthma, Allergy and Airway Center) (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Pilot Study for Speculum Free Cervical Cancer Screening

    NCT04107181

    • Interventional
    • Ages 21 to 65 years
    • Sex: Female
    • Accepts healthy volunteers

    Nearest site: Duke University (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. Duke APOL1 Research Biorepository

    NCT04160507

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

    NCT04278404

    • Observational
    • Ages 0 to 20 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Health System (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension

    NCT04454203

    • Phase 4
    • Ages 18 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Hospital (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. American Lung Association (ALA) Lung Health Cohort

    NCT04543461

    • Observational
    • Ages 25 to 35 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. Neural Correlates of Real World Spatial Navigation in Humans

    NCT04874220

    • Interventional
    • Ages 18 to 90 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2)

    NCT04995341

    • Interventional
    • Ages Any age
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Eye Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. Registry of Arthrex Hand and Wrist Products

    NCT05046600

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans

    NCT05120635

    • Interventional
    • Ages 18 to 70 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Health System (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US

    NCT05129345

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University - Duke Study Site (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. Virtual Reality Visual Field Testing as an Alternative in Childhood Eye Disease

    NCT05150197

    • Interventional
    • Ages 4 to 21 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

    NCT05334069

    • Observational
    • Ages 40 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Durham VA Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  37. Transcranial Magnetic Brain Stimulation to Reduce Cannabis Use in Heavy Cannabis Users

    NCT05401929

    • Interventional
    • Ages 18 to 65 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  38. Prototyping a Device for Automating Stool and Urine Output Tracking

    NCT05438199

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  39. Neuromodulation of Memory in Aging

    NCT05460468

    • Interventional
    • Ages 18 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Hospital (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  40. The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

    NCT05564936

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  41. The WISER Study: Web Based Methods for Enhancing Resilience

    NCT05636072

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Health System (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking

    NCT05665465

    • Early Phase 1
    • Ages 18 to 21 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  43. Mobile Neurofeedback for Low Back Pain

    NCT05669027

    • Interventional
    • Ages 18 to 90 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Medical Center, Department of Psychiatry (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  44. Gathering Online for Dialogue and Discussion to Enhance Social Support

    NCT05753683

    • Interventional
    • Ages 18 to 30 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: RTI International (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  45. Macrophage Regulation of Ozone-Induced Lung Inflammation

    NCT05773001

    • Phase 1
    • Ages 18 to 55 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  46. Cochlear Implants in Young Children With SSD

    NCT05775367

    • Interventional
    • Ages 7 to 71 months
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: The Children's Cochlear Implant Center at UNC (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  47. Supporting Health in Veterans With Heart Failure

    NCT05839067

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: VA Clinic - Durham (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  48. SenseToKnow Autism Screening Device Validation Study

    NCT05874466

    • Observational
    • Ages 16 to 36 months
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  49. Neuroimaging of Opioid Phase (OPAL)

    NCT05905419

    • Interventional
    • Ages 18 years and older
    • Sex: Female
    • Accepts healthy volunteers

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  50. MRI Neurofeedback and Brain Circuits Related to Motivation in Healthy Participants

    NCT05929898

    • Interventional
    • Ages 18 to 45 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Center for Cognitive Neuroscience (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Healthy Volunteers clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.