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Retinal Imaging in Neurodegenerative Disease

NCT03233646

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (UWF) fundus photography to assess the structure and function of the retinal and choroidal microvasculature and structure in persons with mild cognitive impairment (MCI) and Alzheimer's Disease (AD), Parkinson's Disease (PD), or other neurodegenerative disease, diseases as outlined.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Alzheimer's Disease
  • Mild Cognitive Impairment
  • Parkinson's Disease
  • Multiple Sclerosis
  • Huntington Disease
  • Lewy Body Dementia
  • Frontotemporal Dementia
  • Amyotrophic Lateral Sclerosis (ALS)
  • APOE-4 Positive
  • Traumatic Brain Injury
  • Concussion
  • Post-Traumatic Stress Disorder
  • Down Syndrome
  • Neuro-Degenerative Disease
  • Normal Cognition

Eligibility basics and study details

Study type
Observational
Phase
Not applicable
Ages
18 years and older
Sex
All
Healthy volunteers
Accepted
Sponsor
Duke University
Last updated on ClinicalTrials.gov
February 4, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

North Carolina · 1

  • Duke University Medical Center · Durham, NC

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.