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Healthy Volunteers Clinical Trials Recruiting in the US

5,005 studies for Healthy Volunteers are recruiting at 11,548 US sites, according to ClinicalTrials.gov data processed .

Some clinical studies enroll healthy volunteers, people without the condition being studied, to help researchers compare results.

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Recruiting now

Top Healthy Volunteers studies by number of US sites

Showing 30 studies, most US recruiting sites first.
  1. Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

    NCT05334069

    • Observational
    • Ages 40 to 75 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    610 US recruiting sites
  2. Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

    NCT07018869

    • Phase 3
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    374 US recruiting sites
  3. Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

    NCT07283939

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    350 US recruiting sites
  4. Family Communications After Genetic Testing

    NCT07143487

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    346 US recruiting sites
  5. Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

    NCT07091617

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    318 US recruiting sites
  6. A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

    NCT07805707

    • Phase 3
    • Ages 65 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    163 US recruiting sites
  7. A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

    NCT07282665

    • Phase 3
    • Ages 65 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    141 US recruiting sites
  8. A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

    NCT06112418

    • Interventional
    • Ages 55 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    122 US recruiting sites
  9. BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

    NCT07160244

    • Phase 3
    • Ages 1 day to 49 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    116 US recruiting sites
  10. Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

    NCT07215624

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    102 US recruiting sites
  11. A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.

    NCT07629440

    • Phase 3
    • Ages 42 to 211 days
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    95 US recruiting sites
  12. Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

    NCT04262206

    • Phase 4
    • Ages 75 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    89 US recruiting sites
  13. A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose

    NCT06866405

    • Phase 3
    • Ages 0 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    80 US recruiting sites
  14. Galleri® in the Medicare Population.

    NCT05673018

    • Interventional
    • Ages 50 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    61 US recruiting sites
  15. Shield Post-Approval Study Protocol

    NCT06880055

    • Observational
    • Ages 45 to 81 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    58 US recruiting sites
  16. Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents

    NCT07660198

    • Phase 3
    • Ages 15 months to 17 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    53 US recruiting sites
  17. Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

    NCT01574053

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    52 US recruiting sites
  18. Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure

    NCT07775495

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    51 US recruiting sites
  19. A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

    NCT06740630

    • Phase 3
    • Ages 12 to 15 months
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    50 US recruiting sites
  20. Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older

    NCT07734649

    • Phase 1/2
    • Ages 60 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    50 US recruiting sites
  21. Education & Mentorship of Advanced Practice Providers to Increase Community-based Research Within the NCORP Network, COACH-APP Trial

    NCT06904391

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    44 US recruiting sites
  22. Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

    NCT05006482

    • Phase 3
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    43 US recruiting sites
  23. The Vanguard Study: Testing a New Way to Screen for Cancer

    NCT06995898

    • Interventional
    • Ages 45 to 75 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    43 US recruiting sites
  24. A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

    NCT07654374

    • Phase 3
    • Ages 18 to 79 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    43 US recruiting sites
  25. Integrated Cancer Repository for Cancer Research

    NCT02012699

    • Observational
    • Ages 19 to 110 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    42 US recruiting sites
  26. Pancreatic Cancer Early Detection Consortium

    NCT04970056

    • Observational
    • Ages 18 to 90 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    40 US recruiting sites
  27. Caris Biorepository Research Protocol

    NCT01499394

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    38 US recruiting sites
  28. A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent Pneumococcal Conjugate Vaccine Administered to Adults

    NCT07794748

    • Phase 3
    • Ages 18 to 49 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    37 US recruiting sites
  29. Molecular Genetics Studies of Cancer Patients and Their Relatives

    NCT04185935

    • Observational
    • Ages Any age
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    34 US recruiting sites
  30. ASSESS ALL ALS Study

    NCT06578195

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    34 US recruiting sites

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Healthy Volunteers clinical trials by city

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Healthy Volunteers clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.