Family Communications After Genetic Testing
NCT07143487
This study is recruiting at 346 US sites in 32 states, according to its ClinicalTrials.gov record last updated .
Summary
This clinical trial compares patient (proband)-mediated communication to provider-mediated communication for improving genetic testing in first-degree relatives of patients with newly diagnosed colorectal cancer. It is estimated that 30% of cases of colorectal cancer have a genetic basis and about 15% of these patients have a disease-causing (pathogenic) inherited (germline) variant in a cancer susceptibility gene. Most individuals carrying a pathogenic germline variant are unaware of their cancer risk and may not meet guidelines for genetic testing.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Colon Adenocarcinoma
- Colorectal Adenocarcinoma
- Rectal Adenocarcinoma
- Stage I Colon Cancer AJCC v8
- Stage I Colorectal Cancer AJCC v8
- Stage I Rectal Cancer AJCC v8
- Stage II Colon Cancer AJCC v8
- Stage II Colorectal Cancer AJCC v8
- Stage II Rectal Cancer AJCC v8
- Stage III Colon Cancer AJCC v8
- Stage III Colorectal Cancer AJCC v8
- Stage III Rectal Cancer AJCC v8
- Stage IV Colon Cancer AJCC v8
- Stage IV Colorectal Cancer AJCC v8
- Stage IV Rectal Cancer AJCC v8
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Not applicable
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Sponsor
- Alliance for Clinical Trials in Oncology
- Last updated on ClinicalTrials.gov
- October 2, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alaska · 7
- Alaska Breast Care and Surgery LLC · Anchorage, AK
- Alaska Oncology and Hematology LLC · Anchorage, AK
- Alaska Women's Cancer Care · Anchorage, AK
- Anchorage Associates in Radiation Medicine · Anchorage, AK
- Katmai Oncology Group · Anchorage, AK
- Providence Alaska Medical Center · Anchorage, AK
- Fairbanks Memorial Hospital · Fairbanks, AK
Arizona · 1
- Cancer Center at Saint Joseph's · Phoenix, AZ
Arkansas · 2
- Mercy Hospital Fort Smith · Fort Smith, AR
- CARTI Cancer Center · Little Rock, AR
California · 20
- Mission Hope Medical Oncology - Arroyo Grande · Arroyo Grande, CA
- Providence Saint Joseph Medical Center/Disney Family Cancer Center · Burbank, CA
- Marshall Cancer Center · Cameron Park, CA
- Mercy Cancer Center - Carmichael · Carmichael, CA
- Mercy San Juan Medical Center · Carmichael, CA
- Enloe Medical Center · Chico, CA
- Mercy Cancer Center - Elk Grove · Elk Grove, CA
- Fremont - Rideout Cancer Center · Marysville, CA
- Mercy Cancer Center · Merced, CA
- Providence Queen of The Valley · Napa, CA
- Mercy Cancer Center - Rocklin · Rocklin, CA
- Mercy Cancer Center - Sacramento · Sacramento, CA
- Pacific Central Coast Health Center-San Luis Obispo · San Luis Obispo, CA
- Mission Hope Medical Oncology - Santa Maria · Santa Maria, CA
- Providence Medical Foundation - Santa Rosa · Santa Rosa, CA
- Providence Santa Rosa Memorial Hospital · Santa Rosa, CA
- Saint Helena Hospital · St. Helena, CA
- Saint Joseph's Medical Center · Stockton, CA
- Gene Upshaw Memorial Tahoe Forest Cancer Center · Truckee, CA
- Woodland Memorial Hospital · Woodland, CA
Colorado · 9
- Penrose-Saint Francis Healthcare · Colorado Springs, CO
- Rocky Mountain Cancer Centers-Penrose · Colorado Springs, CO
- Saint Francis Cancer Center · Colorado Springs, CO
- CommonSpirit Cancer Center Mercy · Durango, CO
- Mercy Medical Center · Durango, CO
- CommonSpirit Saint Anthony Hospital Cancer Center · Lakewood, CO
- Longmont United Hospital · Longmont, CO
- Saint Mary Corwin Medical Center · Pueblo, CO
- Saint Anthony North Hospital · Westminster, CO
Florida · 1
- Holy Cross Hospital · Fort Lauderdale, FL
Idaho · 12
- Saint Alphonsus Cancer Care Center-Boise · Boise, ID
- Saint Luke's Cancer Institute - Boise · Boise, ID
- Saint Alphonsus Cancer Care Center-Caldwell · Caldwell, ID
- Kootenai Health - Coeur d'Alene · Coeur d'Alene, ID
- Saint Luke's Cancer Institute - Fruitland · Fruitland, ID
- Idaho Urologic Institute-Meridian · Meridian, ID
- Saint Luke's Cancer Institute - Meridian · Meridian, ID
- Saint Alphonsus Cancer Care Center-Nampa · Nampa, ID
- Saint Luke's Cancer Institute - Nampa · Nampa, ID
- Kootenai Clinic Cancer Services - Post Falls · Post Falls, ID
- Kootenai Clinic Cancer Services - Sandpoint · Sandpoint, ID
- Saint Luke's Cancer Institute - Twin Falls · Twin Falls, ID
Illinois · 49
- OSF Saint Anthony's Health Center · Alton, IL
- Advocate Outpatient Center - Aurora · Aurora, IL
- Advocate Good Shepherd Hospital · Barrington, IL
- Illinois CancerCare-Bloomington · Bloomington, IL
- Illinois CancerCare-Canton · Canton, IL
- Memorial Hospital of Carbondale · Carbondale, IL
- SIH Cancer Institute · Carterville, IL
- Illinois CancerCare-Carthage · Carthage, IL
- Centralia Oncology Clinic · Centralia, IL
- Advocate Illinois Masonic Medical Center · Chicago, IL
- AMG Crystal Lake - Oncology · Crystal Lake, IL
- Carle at The Riverfront · Danville, IL
- Cancer Care Specialists of Illinois - Decatur · Decatur, IL
- Decatur Memorial Hospital · Decatur, IL
- Illinois CancerCare-Dixon · Dixon, IL
- Advocate Good Samaritan Hospital · Downers Grove, IL
- Carle Physician Group-Effingham · Effingham, IL
- Crossroads Cancer Center · Effingham, IL
- Advocate Sherman Hospital · Elgin, IL
- Illinois CancerCare-Eureka · Eureka, IL
- Illinois CancerCare-Galesburg · Galesburg, IL
- Advocate South Suburban Hospital · Hazel Crest, IL
- Illinois CancerCare-Kewanee Clinic · Kewanee, IL
- AMG Libertyville - Oncology · Libertyville, IL
- Condell Memorial Hospital · Libertyville, IL
- Illinois CancerCare-Macomb · Macomb, IL
- Carle Physician Group-Mattoon/Charleston · Mattoon, IL
- SSM Health Good Samaritan · Mount Vernon, IL
- Carle BroMenn Medical Center · Normal, IL
- Carle Cancer Institute Normal · Normal, IL
- Cancer Care Center of O'Fallon · O'Fallon, IL
- HSHS Saint Elizabeth's Hospital · O'Fallon, IL
- Advocate Christ Medical Center · Oak Lawn, IL
- Advocate Outpatient Center - Oak Lawn · Oak Lawn, IL
- Illinois CancerCare-Ottawa Clinic · Ottawa, IL
- Advocate High Tech Medical Park · Palos Heights, IL
- Advocate Lutheran General Hospital · Park Ridge, IL
- Illinois CancerCare-Pekin · Pekin, IL
- Illinois CancerCare-Peoria · Peoria, IL
- Methodist Medical Center of Illinois · Peoria, IL
- Illinois CancerCare-Peru · Peru, IL
- Valley Radiation Oncology · Peru, IL
- Illinois CancerCare-Princeton · Princeton, IL
- OSF Saint Anthony Medical Center · Rockford, IL
- Southern Illinois University School of Medicine · Springfield, IL
- Springfield Clinic · Springfield, IL
- Springfield Memorial Hospital · Springfield, IL
- Carle Cancer Center · Urbana, IL
- Illinois CancerCare - Washington · Washington, IL
Indiana · 1
- Reid Health · Richmond, IN
Iowa · 3
- Mercy Cancer Center-West Lakes · Clive, IA
- Mercy Medical Center - Des Moines · Des Moines, IA
- Mercy Medical Center-West Lakes · West Des Moines, IA
Kansas · 4
- Central Care Cancer Center - Garden City · Garden City, KS
- Central Care Cancer Center - Great Bend · Great Bend, KS
- Mercy Hospital Pittsburg · Pittsburg, KS
- Cotton O'Neil Cancer Center / Stormont Vail Health · Topeka, KS
Kentucky · 7
- CommonSpirit Saint Joseph Hospital - Bardstown · Bardstown, KY
- Commonwealth Cancer Center-Corbin · Corbin, KY
- CommonSpirit Saint Joseph Hospital - Lexington · Lexington, KY
- CommonSpirit Saint Joseph Medical Center - East Lexington · Lexington, KY
- Saint Joseph Radiation Oncology Resource Center · Lexington, KY
- CommonSpirit Saint Joseph Hospital London · London, KY
- CommonSpirit Saint Joseph Hospital Mount Sterling · Mount Sterling, KY
Maryland · 4
- Sinai Hospital of Baltimore · Baltimore, MD
- Northwest Hospital Center · Randallstown, MD
- UM Saint Joseph Medical Center · Towson, MD
- William E Kahlert Regional Cancer Center/Sinai Hospital · Westminster, MD
Michigan · 30
- MyMichigan Medical Center Gratiot · Alma, MI
- MyMichigan Medical Center Alpena · Alpena, MI
- Trinity Health Saint Joseph Mercy Hospital Ann Arbor · Ann Arbor, MI
- Bronson Battle Creek · Battle Creek, MI
- Trinity Health IHA Medical Group Hematology Oncology - Brighton · Brighton, MI
- Trinity Health Medical Center - Brighton · Brighton, MI
- Trinity Health IHA Medical Group Hematology Oncology - Canton · Canton, MI
- Trinity Health Medical Center - Canton · Canton, MI
- Chelsea Hospital · Chelsea, MI
- Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital · Chelsea, MI
- Hematology Oncology Consultants-Clarkston · Clarkston, MI
- Trinity Health IHA Medical Group - Primary Care - Clarkston · Clarkston, MI
- Henry Ford Health Saint John Hospital · Detroit, MI
- Cancer Hematology Centers - Flint · Flint, MI
- Genesee Hematology Oncology PC · Flint, MI
- Genesys Hurley Cancer Institute · Flint, MI
- Hurley Medical Center · Flint, MI
- MyMichigan Medical Center Gladwin · Gladwin, MI
- Corewell Health Grand Rapids Hospitals - Butterworth Hospital · Grand Rapids, MI
- Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital · Grand Rapids, MI
- Trinity Health Grand Rapids Hospital · Grand Rapids, MI
- Henry Ford Saint John Hospital - Academic · Grosse Pointe Woods, MI
- Henry Ford Saint John Hospital - Breast · Grosse Pointe Woods, MI
- Henry Ford Saint John Hospital - Van Elslander · Grosse Pointe Woods, MI
- Bronson Methodist Hospital · Kalamazoo, MI
- West Michigan Cancer Center · Kalamazoo, MI
- University of Michigan Health - Sparrow Lansing · Lansing, MI
- Trinity Health Saint Mary Mercy Livonia Hospital · Livonia, MI
- Henry Ford Saint John Hospital - Macomb Medical · Macomb, MI
- Henry Ford Warren Hospital - Breast Macomb · Macomb, MI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.