Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
NCT07283939
This study is recruiting at 350 US sites in 38 states, according to its ClinicalTrials.gov record last updated .
Summary
This study seeks to learn whether using the PAGODA algorithm to guide chemotherapy dosing will lower the chance of unplanned delays during chemotherapy for cancer in the gastrointestinal system compared to usual care.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Ampulla of Vater Carcinoma
- Appendix Carcinoma
- Carcinoma of Unknown Primary With Gastrointestinal Profile
- Colon Carcinoma
- Esophageal Carcinoma
- Gastric Carcinoma
- Gastroesophageal Junction Carcinoma
- Malignant Digestive System Neoplasm
- Rectal Carcinoma
- Small Intestinal Carcinoma
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Not applicable
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Sponsor
- Alliance for Clinical Trials in Oncology
- Last updated on ClinicalTrials.gov
- October 2, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alaska · 1
- Fairbanks Memorial Hospital · Fairbanks, AK
Arizona · 1
- Cancer Center at Saint Joseph's · Phoenix, AZ
Arkansas · 3
- Mercy Hospital Fort Smith · Fort Smith, AR
- NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro · Jonesboro, AR
- CARTI Cancer Center · Little Rock, AR
California · 11
- Mission Hope Medical Oncology - Arroyo Grande · Arroyo Grande, CA
- Mercy Cancer Center - Carmichael · Carmichael, CA
- Mercy San Juan Medical Center · Carmichael, CA
- Mercy Cancer Center - Elk Grove · Elk Grove, CA
- Mercy Cancer Center · Merced, CA
- Mercy Cancer Center - Rocklin · Rocklin, CA
- Mercy Cancer Center - Sacramento · Sacramento, CA
- Pacific Central Coast Health Center-San Luis Obispo · San Luis Obispo, CA
- Mission Hope Medical Oncology - Santa Maria · Santa Maria, CA
- Saint Joseph's Medical Center · Stockton, CA
- Woodland Memorial Hospital · Woodland, CA
Colorado · 9
- Penrose-Saint Francis Healthcare · Colorado Springs, CO
- Rocky Mountain Cancer Centers-Penrose · Colorado Springs, CO
- Saint Francis Cancer Center · Colorado Springs, CO
- CommonSpirit Cancer Center Mercy · Durango, CO
- Mercy Medical Center · Durango, CO
- CommonSpirit Saint Anthony Hospital Cancer Center · Lakewood, CO
- Longmont United Hospital · Longmont, CO
- Saint Mary Corwin Medical Center · Pueblo, CO
- Saint Anthony North Hospital · Westminster, CO
Delaware · 7
- Beebe Medical Center · Lewes, DE
- Beebe South Coastal Health Campus · Millville, DE
- Christiana Care Health System-Christiana Hospital · Newark, DE
- Helen F Graham Cancer Center · Newark, DE
- Medical Oncology Hematology Consultants PA · Newark, DE
- Beebe Health Campus · Rehoboth Beach, DE
- Christiana Care Health System-Wilmington Hospital · Wilmington, DE
Florida · 1
- Holy Cross Hospital · Fort Lauderdale, FL
Georgia · 2
- Northside Hospital · Atlanta, GA
- Tift Regional Medical Center · Tifton, GA
Idaho · 7
- Saint Alphonsus Cancer Care Center-Boise · Boise, ID
- Saint Alphonsus Cancer Care Center-Caldwell · Caldwell, ID
- Kootenai Health - Coeur d'Alene · Coeur d'Alene, ID
- Idaho Urologic Institute-Meridian · Meridian, ID
- Saint Alphonsus Cancer Care Center-Nampa · Nampa, ID
- Kootenai Clinic Cancer Services - Post Falls · Post Falls, ID
- Kootenai Clinic Cancer Services - Sandpoint · Sandpoint, ID
Illinois · 34
- OSF Saint Anthony's Health Center · Alton, IL
- Illinois CancerCare-Bloomington · Bloomington, IL
- Illinois CancerCare-Canton · Canton, IL
- Memorial Hospital of Carbondale · Carbondale, IL
- SIH Cancer Institute · Carterville, IL
- Illinois CancerCare-Carthage · Carthage, IL
- Centralia Oncology Clinic · Centralia, IL
- Carle at The Riverfront · Danville, IL
- Cancer Care Specialists of Illinois - Decatur · Decatur, IL
- Decatur Memorial Hospital · Decatur, IL
- Illinois CancerCare-Dixon · Dixon, IL
- Carle Physician Group-Effingham · Effingham, IL
- Crossroads Cancer Center · Effingham, IL
- Illinois CancerCare-Eureka · Eureka, IL
- Illinois CancerCare-Galesburg · Galesburg, IL
- Illinois CancerCare-Kewanee Clinic · Kewanee, IL
- Illinois CancerCare-Macomb · Macomb, IL
- Carle Physician Group-Mattoon/Charleston · Mattoon, IL
- SSM Health Good Samaritan · Mount Vernon, IL
- Carle BroMenn Medical Center · Normal, IL
- Carle Cancer Institute Normal · Normal, IL
- Cancer Care Center of O'Fallon · O'Fallon, IL
- HSHS Saint Elizabeth's Hospital · O'Fallon, IL
- Illinois CancerCare-Ottawa Clinic · Ottawa, IL
- Illinois CancerCare-Pekin · Pekin, IL
- Illinois CancerCare-Peoria · Peoria, IL
- Illinois CancerCare-Peru · Peru, IL
- Valley Radiation Oncology · Peru, IL
- Illinois CancerCare-Princeton · Princeton, IL
- Southern Illinois University School of Medicine · Springfield, IL
- Springfield Clinic · Springfield, IL
- Springfield Memorial Hospital · Springfield, IL
- Carle Cancer Center · Urbana, IL
- Illinois CancerCare - Washington · Washington, IL
Indiana · 8
- Northwest Cancer Center - Crown Point · Crown Point, IN
- Northwest Oncology LLC · Dyer, IN
- Northwest Cancer Center - Hobart · Hobart, IN
- Saint Mary Medical Center · Hobart, IN
- Saint Catherine Hospital · Indianapolis, IN
- The Community Hospital · Munster, IN
- Women's Diagnostic Center - Munster · Munster, IN
- Northwest Cancer Center - Valparaiso · Valparaiso, IN
Iowa · 15
- Mary Greeley Medical Center · Ames, IA
- McFarland Clinic - Ames · Ames, IA
- UI Health Care Mission Cancer and Blood - Ankeny Clinic · Ankeny, IA
- Mercy Hospital · Cedar Rapids, IA
- Oncology Associates at Mercy Medical Center · Cedar Rapids, IA
- Mercy Cancer Center-West Lakes · Clive, IA
- Broadlawns Medical Center · Des Moines, IA
- Iowa Methodist Medical Center · Des Moines, IA
- Mercy Medical Center - Des Moines · Des Moines, IA
- UI Health Care Mission Cancer and Blood - Des Moines Clinic · Des Moines, IA
- UI Health Care Mission Cancer and Blood - Laurel Clinic · Des Moines, IA
- McFarland Clinic - Trinity Cancer Center · Fort Dodge, IA
- McFarland Clinic - Marshalltown · Marshalltown, IA
- UI Health Care Mission Cancer and Blood - Waukee Clinic · Waukee, IA
- Mercy Medical Center-West Lakes · West Des Moines, IA
Kansas · 13
- University of Kansas Clinical Research Center · Fairway, KS
- Central Care Cancer Center - Garden City · Garden City, KS
- Central Care Cancer Center - Great Bend · Great Bend, KS
- HaysMed · Hays, KS
- University of Kansas Cancer Center · Kansas City, KS
- Lawrence Memorial Hospital · Lawrence, KS
- The University of Kansas Cancer Center - Olathe · Olathe, KS
- University of Kansas Cancer Center-Overland Park · Overland Park, KS
- University of Kansas Hospital-Indian Creek Campus · Overland Park, KS
- Mercy Hospital Pittsburg · Pittsburg, KS
- Salina Regional Health Center · Salina, KS
- University of Kansas Health System Saint Francis Campus · Topeka, KS
- University of Kansas Hospital-Westwood Cancer Center · Westwood, KS
Kentucky · 7
- CommonSpirit Saint Joseph Hospital - Bardstown · Bardstown, KY
- Commonwealth Cancer Center-Corbin · Corbin, KY
- CommonSpirit Saint Joseph Hospital - Lexington · Lexington, KY
- CommonSpirit Saint Joseph Medical Center - East Lexington · Lexington, KY
- Saint Joseph Radiation Oncology Resource Center · Lexington, KY
- CommonSpirit Saint Joseph Hospital London · London, KY
- CommonSpirit Saint Joseph Hospital Mount Sterling · Mount Sterling, KY
Louisiana · 2
- Ochsner Hematology Oncology North Shore - Covington (West Region) · Covington, LA
- Ochsner Medical Center Jefferson · New Orleans, LA
Maine · 5
- MaineHealth Cancer Care and IV Therapy - Brunswick · Brunswick, ME
- MaineHealth LincolnHealth Hospital · Damariscotta, ME
- MaineHealth Cancer Care Center of York County · Sanford, ME
- MaineHealth Maine Medical Center- Scarborough · Scarborough, ME
- MaineHealth Cancer Care and IV Therapy - South Portland · South Portland, ME
Maryland · 1
- Christiana Care - Union Hospital · Elkton, MD
Michigan · 23
- MyMichigan Medical Center Gratiot · Alma, MI
- MyMichigan Medical Center Alpena · Alpena, MI
- Trinity Health IHA - Obstetrics and Gynecology West Arbor · Ann Arbor, MI
- Trinity Health Saint Joseph Mercy Hospital Ann Arbor · Ann Arbor, MI
- Bronson Battle Creek · Battle Creek, MI
- Trinity Health IHA Medical Group Hematology Oncology - Brighton · Brighton, MI
- Trinity Health Medical Center - Brighton · Brighton, MI
- Trinity Health IHA Medical Group Hematology Oncology - Canton · Canton, MI
- Trinity Health Medical Center - Canton · Canton, MI
- Chelsea Hospital · Chelsea, MI
- Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital · Chelsea, MI
- Hematology Oncology Consultants-Clarkston · Clarkston, MI
- Trinity Health IHA Medical Group - Primary Care - Clarkston · Clarkston, MI
- Henry Ford Health Saint John Hospital · Detroit, MI
- OSF Saint Francis Hospital and Medical Group · Escanaba, MI
- Cancer Hematology Centers - Flint · Flint, MI
- Genesee Hematology Oncology PC · Flint, MI
- Genesys Hurley Cancer Institute · Flint, MI
- Hurley Medical Center · Flint, MI
- MyMichigan Medical Center Gladwin · Gladwin, MI
- Corewell Health Grand Rapids Hospitals - Butterworth Hospital · Grand Rapids, MI
- Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital · Grand Rapids, MI
- Trinity Health Grand Rapids Hospital · Grand Rapids, MI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.