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Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans

NCT05120635

This study is recruiting at 2 US sites in 2 states, according to its ClinicalTrials.gov record last updated .

Summary

Anxiety disorders such as post-traumatic stress disorder (PTSD) and generalized anxiety disorder (GAD) affect a large number of individuals with a significant portion of patients failing to improve with current treatments. The purpose of this study is to understand the brain mechanisms that produce fear and anxiety in humans. To accomplish this goal, we will measure the brain activity along with the heart rate and skin perspiration of patients while they are completing tasks on a computer.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Fear
  • GAD
  • Emotional Memory
  • PTSD

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
18 to 70 years
Sex
All
Healthy volunteers
Accepted
Sponsor
Duke University
Last updated on ClinicalTrials.gov
August 31, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 1

  • University of California Los Angeles · Los Angeles, CA

North Carolina · 1

  • Duke University Health System · Durham, NC

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.