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Parkinson's Disease Clinical Trials Recruiting in the US

216 studies for Parkinson's Disease are recruiting at 650 US sites, according to ClinicalTrials.gov data processed .

Parkinson's disease is a progressive brain disorder that affects movement and can cause tremor, stiffness and slowness.

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Recruiting now

Top Parkinson's Disease studies by number of US sites

Showing 30 studies, most US recruiting sites first.
  1. A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

    NCT07174310

    • Phase 3
    • Ages 50 to 85 years
    • Sex: All
    Recruiting sites
    53 US recruiting sites
  2. Parkinson's Foundation PD GENEration Genetic Registry

    NCT04994015

    • Observational
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    49 US recruiting sites
  3. A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

    NCT06680830

    • Phase 2
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    44 US recruiting sites
  4. A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

    NCT06944522

    • Phase 3
    • Ages 45 to 75 years
    • Sex: All
    Recruiting sites
    34 US recruiting sites
  5. PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

    NCT04477785

    • Observational
    • Ages 30 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    30 US recruiting sites
  6. A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

    NCT07432958

    • Phase 2
    • Ages 30 to 80 years
    • Sex: All
    Recruiting sites
    30 US recruiting sites
  7. A Study of Buntanetap in Participants With PD

    NCT07284784

    • Phase 2/3
    • Ages 40 to 85 years
    • Sex: All
    Recruiting sites
    27 US recruiting sites
  8. A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease

    NCT06976268

    • Phase 2/3
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    24 US recruiting sites
  9. A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease

    NCT06765668

    • Phase 4
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    23 US recruiting sites
  10. Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

    NCT02071134

    • Observational
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    19 US recruiting sites
  11. Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

    NCT06719583

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    11 US recruiting sites
  12. Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis

    NCT04373317

    • Phase 4
    • Ages 40 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    9 US recruiting sites
  13. A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease

    NCT06809400

    • Phase 1
    • Ages 30 to 85 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    9 US recruiting sites
  14. Abbott DBS Post-Market Study of Outcomes for Indications Over Time

    NCT04071847

    • Observational
    • Ages Any age
    • Sex: All
    Recruiting sites
    8 US recruiting sites
  15. Deep Brain Stimulation (DBS) Retrospective Outcomes Study

    NCT03664609

    • Observational
    • Ages Any age
    • Sex: All
    Recruiting sites
    7 US recruiting sites
  16. A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease

    NCT04991831

    • Observational
    • Ages 30 to 99 years
    • Sex: All
    Recruiting sites
    7 US recruiting sites
  17. Use of CereGate Therapy for Freezing of Gait in PD

    NCT05292794

    • Interventional
    • Ages 21 to 80 years
    • Sex: All
    Recruiting sites
    7 US recruiting sites
  18. A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications

    NCT07330258

    • Observational
    • Ages 45 to 75 years
    • Sex: All
    Recruiting sites
    7 US recruiting sites
  19. The Parkinson's Genetic Research Study

    NCT01558479

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    5 US recruiting sites
  20. Natural History Study of Synucleinopathies

    NCT01799915

    • Observational
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    5 US recruiting sites
  21. Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease

    NCT07005180

    • Phase 2
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    5 US recruiting sites
  22. Real-World Patient Experiences Using Continuous Subcutaneous Apomorphine Infusion (ONAPGOTM) in the United States:

    NCT07219927

    • Observational
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    5 US recruiting sites
  23. Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease

    NCT05266417

    • Phase 2
    • Ages 30 years and older
    • Sex: All
    Recruiting sites
    4 US recruiting sites
  24. A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

    NCT05539196

    • Observational
    • Ages 30 to 99 years
    • Sex: All
    Recruiting sites
    4 US recruiting sites
  25. Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease

    NCT07207122

    • Interventional
    • Ages 22 to 80 years
    • Sex: All
    Recruiting sites
    4 US recruiting sites
  26. GBPDC: Gut-Brain in PD Consortium Master Protocol

    NCT07567794

    • Observational
    • Ages 21 to 80 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    4 US recruiting sites
  27. Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers

    NCT05395624

    • Phase 1/2
    • Ages 18 to 80 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    3 US recruiting sites
  28. Study of Biodistribution, Metabolism, Excretion and Brain Uptake11C-M503

    NCT06303921

    • Early Phase 1
    • Ages 40 to 85 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    3 US recruiting sites
  29. SAD Study in Patients With Parkinson's Disease and Motor Fluctuations

    NCT07422675

    • Phase 1
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    3 US recruiting sites
  30. A Novel Digital Music-based Autonomous Personalized Walking Intervention to Improve Gait and Walking Automaticity in Parkinson Disease

    NCT07705373

    • Interventional
    • Ages 40 years and older
    • Sex: All
    Recruiting sites
    3 US recruiting sites

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Parkinson's Disease clinical trials by city

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Parkinson's Disease clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.