A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
NCT07174310
This study is recruiting at 53 US sites in 29 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics (PK) of prasinezumab compared with placebo in participants with early-stage Parkinson's disease (PD) on stable symptomatic monotherapy with levodopa.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Parkinson's Disease
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 50 to 85 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Hoffmann-La Roche
- Last updated on ClinicalTrials.gov
- October 6, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- University of Alabama at Birmingham · Birmingham, AL
Arizona · 1
- Barrow Neurological Institute · Phoenix, AZ
California · 8
- Neurology Center of North Orange County · Fullerton, CA
- UC San Diego · La Jolla, CA
- Keck School of Medicine of USC · Los Angeles, CA
- UCLA Neurology Outpatient Clinic · Los Angeles, CA
- Parkinson?s Research Centers of America ? Palo Alto · Palo Alto, CA
- Profound Research LLC at The Neurology Center of Southern California · Pasadena, CA
- UCSF Weill Institute for Neurosciences · San Francisco, CA
- Stanford Neuroscience Health Center (SNHC) · Stanford, CA
Colorado · 1
- Rocky Mountain Movement Disorders · Englewood, CO
Connecticut · 1
- Institute for Neurodegenerative Disorders · New Haven, CT
District of Columbia · 1
- Georgetown University · Washington D.C., DC
Florida · 8
- JEM Research LLC · Atlantis, FL
- Parkinson's Disease and Movement Disorders Center of Boca Raton · Boca Raton, FL
- K2 - Villages · Lady Lake, FL
- K2 Medical Research-Maitland · Maitland, FL
- Baptist Hospital of Miami · Miami, FL
- Advent Health Orlando · Orlando, FL
- Charter Research - Winter Park/Orlando · Orlando, FL
- USF Parkinsons Disease and Movement Disorders Center · Tampa, FL
Georgia · 1
- Grady Memorial Hospital · Atlanta, GA
Hawaii · 1
- Hawaii Pacific Neuroscience · Honolulu, HI
Illinois · 1
- Northwestern University Feinberg School Of Medicine · Chicago, IL
Kansas · 1
- University of Kansas Medical Center · Kansas City, KS
Massachusetts · 1
- Massachusetts General Hospital · Boston, MA
Michigan · 1
- Quest Research Institute · Farmington Hills, MI
Missouri · 1
- Washington Uni School of Medicine · St Louis, MO
Nevada · 2
- Cleveland Clinic Lou Ruvo · Las Vegas, NV
- Renown Health · Reno, NV
New Jersey · 1
- Hackensack University Medical Center;Department of Neurology, Neuroscience Institute · Paramus, NJ
New Mexico · 1
- University of New Mexico · Albuquerque, NM
New York · 4
- Dent Neurological Institute · Amherst, NY
- Parkinson's Research Centers of America - Long Island · Commack, NY
- Columbia University Medical Center · New York, NY
- Weill Cornell Medical College · New York, NY
North Carolina · 2
- Asheville Neurology · Asheville, NC
- Duke University Medical Center · Durham, NC
Ohio · 2
- NeuroCare Center · Canton, OH
- Cleveland Clinic · Cleveland, OH
Oklahoma · 1
- The Movement Disorder Clinic of Oklahoma · Tulsa, OK
Oregon · 1
- Oregon Health and Science University · Portland, OR
Pennsylvania · 2
- University Pennsylvania Hospital · Philadelphia, PA
- Allegheny General Hospital · Pittsburgh, PA
South Dakota · 1
- Avera Medical Group · Sioux Falls, SD
Tennessee · 2
- Veracity Neuroscience · Memphis, TN
- Vanderbilt University Medical Center · Nashville, TN
Texas · 2
- Texas Neurology PA · Dallas, TX
- Central Texas Neurology Consultants · Round Rock, TX
Vermont · 1
- University of Vermont Medical Center · Burlington, VT
Virginia · 2
- University of Virginia Health System · Charlottesville, VA
- VCU Health North Hospital · Richmond, VA
West Virginia · 1
- West Virginia University · Morgantown, WV
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.