PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
NCT04477785
This study is recruiting at 30 US sites in 19 states, according to its ClinicalTrials.gov record last updated .
Summary
The Parkinson Progression Marker Initiative (PPMI) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease (PD) progression in study participants with manifest PD, prodromal PD, and healthy controls. The overall goal of PPMI is to identify markers of disease progression for use in clinical trials of therapies to reduce progression of PD disability.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Parkinson Disease
Eligibility basics and study details
- Study type
- Observational
- Phase
- Not applicable
- Ages
- 30 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Sponsor
- Michael J. Fox Foundation for Parkinson's Research
- Last updated on ClinicalTrials.gov
- July 27, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- University of Alabama at Birmingham · Birmingham, AL
Arizona · 3
- Barrow Neurological Institute · Phoenix, AZ
- Mayo Foundation for Medical Education and Research · Scottsdale, AZ
- Banner Research Institute · Sun City, AZ
California · 3
- University of California San Diego · La Jolla, CA
- Keck School of Medicine of USC · Los Angeles, CA
- University of California, San Francisco · San Francisco, CA
Colorado · 1
- University of Colorado Anschutz Medical Campus · Aurora, CO
Connecticut · 1
- Institute For Neurodegenerative Disorders · New Haven, CT
Florida · 3
- Parkinson's Disease& Movement Disorder Center of Boca Raton · Boca Raton, FL
- University of Florida · Gainesville, FL
- University of South Florida · Tampa, FL
Georgia · 1
- Emory University School of Medicine · Atlanta, GA
Illinois · 1
- Northwestern University · Chicago, IL
Kansas · 1
- University of Kansas Medical Center · Kansas City, KS
Maryland · 1
- Johns Hopkins University · Baltimore, MD
Massachusetts · 2
- Boston University · Boston, MA
- Massachusetts General Hospital · Boston, MA
Michigan · 1
- University of Michigan · Ann Arbor, MI
Nevada · 1
- Cleveland Clinic Lou Ruvo Center for Brain Health · Las Vegas, NV
New York · 3
- Beth Israel Medical Center · New York, NY
- NYU Langone Health · New York, NY
- University of Rochester · Rochester, NY
Ohio · 2
- University of Cincinnati/Cincinnati Children's Hospital · Cincinnati, OH
- Cleveland Clinic · Cleveland, OH
Oregon · 1
- Oregon Health &Science University · Portland, OR
Pennsylvania · 2
- University of Pennsylvania · Philadelphia, PA
- University of Pittsburgh · Pittsburgh, PA
Texas · 1
- Baylor College of Medicine · Houston, TX
Washington · 1
- Univ of Washington and VA Puget Sound Health Care System · Seattle, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.