Osteoarthritis Clinical Trials Recruiting in the US
162 studies for Osteoarthritis are recruiting at 511 US sites, according to ClinicalTrials.gov data processed .
Osteoarthritis is the most common form of arthritis and happens when the cartilage that cushions the ends of bones wears down over time.
Recruiting now
Top Osteoarthritis studies by number of US sites
Showing 30 studies, most US recruiting sites first.
- Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
NCT07353931
- Phase 3
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 38 US recruiting sites
- A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain
NCT07641517
- Phase 2
- Ages 40 years and older
- Sex: All
- Recruiting sites
- 36 US recruiting sites
- A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
NCT05986292
- Phase 2
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 35 US recruiting sites
- Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis
NCT07339111
- Phase 3
- Ages 18 to 75 years
- Sex: All
- Recruiting sites
- 31 US recruiting sites
- Exactech Shoulder Post Market Clinical Follow-up Study
NCT05603728
- Observational
- Ages 21 years and older
- Sex: All
- Recruiting sites
- 24 US recruiting sites
- Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain
NCT07226258
- Phase 3
- Ages 40 years and older
- Sex: All
- Recruiting sites
- 22 US recruiting sites
- A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
NCT07481630
- Phase 3
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 19 US recruiting sites
- AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
NCT07509307
- Phase 3
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 18 US recruiting sites
- Recruiting sites
- 15 US recruiting sites
- Recruiting sites
- 13 US recruiting sites
- Preventing Injured Knees From osteoArthritis: Severity Outcomes
NCT06096259
- Phase 2
- Ages 18 to 45 years
- Sex: All
- Recruiting sites
- 9 US recruiting sites
- A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients
NCT07219771
- Phase 3
- Ages 40 to 80 years
- Sex: All
- Recruiting sites
- 8 US recruiting sites
- MaioRegen Prime Study for the Treatment of Deep Osteochondral Lesion of the Knee
NCT07332182
- Interventional
- Ages 18 to 60 years
- Sex: All
- Recruiting sites
- 8 US recruiting sites
- Recruiting sites
- 7 US recruiting sites
- A Multicenter, Postmarket Surveillance Study of Subjects With the Canary canturioTM te Tibial Extension
NCT06040827
- Observational
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 6 US recruiting sites
- Recruiting sites
- 6 US recruiting sites
- Recruiting sites
- 5 US recruiting sites
- Recruiting sites
- 5 US recruiting sites
- Recruiting sites
- 5 US recruiting sites
- Evaluation of the Patellar LIFT System for Subjects With Patellofemoral Cartilage Degeneration
NCT06423300
- Interventional
- Ages 22 to 65 years
- Sex: All
- Recruiting sites
- 5 US recruiting sites
- Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Knee Osteoarthritis
NCT06608134
- Early Phase 1
- Ages 30 years and older
- Sex: All
- Recruiting sites
- 5 US recruiting sites
- A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System
NCT07118501
- Observational
- Ages 21 years and older
- Sex: All
- Recruiting sites
- 5 US recruiting sites
- Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection
NCT07804446
- Interventional
- Ages 40 years and older
- Sex: All
- Recruiting sites
- 5 US recruiting sites
- Clinical Outcomes Study of the Nexel Total Elbow
NCT02469662
- Interventional
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 4 US recruiting sites
- Ketorolac in Upper Extremity Tendinopathy and Arthropathy
NCT05292339
- Phase 4
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 4 US recruiting sites
- The KinematX Midcarpal Total Wrist Arthroplasty Registry
NCT05719935
- Observational
- Ages 18 to 85 years
- Sex: All
- Recruiting sites
- 4 US recruiting sites
- Recruiting sites
- 4 US recruiting sites
- Recruiting sites
- 4 US recruiting sites
- Intra-Articular Allocetra in Patients With Primary Knee Osteoarthritis
NCT07580716
- Phase 2
- Ages 64 years and older
- Sex: All
- Recruiting sites
- 4 US recruiting sites
- Physica System Total Knee Replacement Registry Study
NCT03048201
- Interventional
- Ages 22 years and older
- Sex: All
- Recruiting sites
- 3 US recruiting sites
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Osteoarthritis clinical trials by city
FAQ
Common questions
What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining an Osteoarthritis clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.