A Study to Learn About Study Medicine Called Berobenatide in Adults With Knee Pain and Overweight or Obesity (VESPER-OA 1)
NCT07919678
This study is recruiting at 7 US sites in 4 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this clinical study is to learn about the safety and effects of berobenatide (PF-08653944) for the treatment of knee osteoarthritis in adults with overweight or obesity. The study will last 52 weeks and compare the effects of berobenatide compared to placebo on knee pain, physical function, and body weight. Study activities will include blood tests, knee pain assessment, physical function questionnaires and body measurements.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Obesity
- Overweight
- Osteoarthritis of the Knee
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Pfizer
- Last updated on ClinicalTrials.gov
- November 5, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Florida · 1
- Universal Axon Clinical Research LLC · Doral, FL
Michigan · 2
- Profound Research LLC · Farmington Hills, MI
- Revive Research Institute, Inc. · Sterling Heights, MI
North Carolina · 3
- Monroe Biomedical Research · Monroe, NC
- Accellacare · Wilmington, NC
- Delaney Radiologist · Wilmington, NC
Pennsylvania · 1
- Altoona Center For Clinical Research · Duncansville, PA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.