A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients
NCT07219771
This study is recruiting at 8 US sites in 7 states, according to its ClinicalTrials.gov record last updated .
Summary
This is a multicenter, prospective, randomized, double-blind, placebo-controlled, parallel-arm, Phase 3 study of intra-articular administration of PTP-001 (MOTYS) for the treatment of knee osteoarthritis. The purpose of the trial is to evaluate the efficacy, safety, and tolerability of a single intra-articular injection of PTP-001 compared to placebo over a 52-week period in participants with radiographic and symptomatic knee OA.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Knee Osteoarthritis
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 40 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Doron Therapeutics Inc.
- Last updated on ClinicalTrials.gov
- April 29, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- Central Research Associates, LLC dba Flourish Research · Birmingham, AL
California · 2
- Horizon Clinical Research · La Mesa, CA
- Focus Clinical Research · West Hills, CA
Florida · 1
- Conquest Research, LLC · Winter Park, FL
Illinois · 1
- Chicago Clinical Research Institute, Inc. · Chicago, IL
Pennsylvania · 1
- Lehigh Center for Clinical Research · Allentown, PA
South Carolina · 1
- Coastal Carolina Research Center, LLD · North Charleston, SC
Utah · 1
- JBR Clinical Research, LLC · Salt Lake City, UT
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.