High Blood Pressure Clinical Trials Recruiting in the US
192 studies for High Blood Pressure are recruiting at 1,113 US sites, according to ClinicalTrials.gov data processed .
High blood pressure (hypertension) is a common condition in which the force of blood against the artery walls stays higher than normal.
Recruiting now
Top High Blood Pressure studies by number of US sites
Showing 30 studies, most US recruiting sites first.
- Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
NCT07181109
- Phase 3
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 263 US recruiting sites
- EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473
- Phase 3
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 201 US recruiting sites
- A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
NCT06742723
- Phase 3
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 116 US recruiting sites
- Global Paradise System US Post Approval Study
NCT06297291
- Observational
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 42 US recruiting sites
- THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
NCT06559891
- Interventional
- Ages 22 to 75 years
- Sex: All
- Recruiting sites
- 34 US recruiting sites
- A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
NCT07142356
- Phase 2
- Ages 18 to 75 years
- Sex: All
- Recruiting sites
- 33 US recruiting sites
- A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia
NCT07610278
- Phase 2
- Ages 18 to 75 years
- Sex: All
- Recruiting sites
- 29 US recruiting sites
- A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
NCT07783802
- Phase 2
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 29 US recruiting sites
- To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension
NCT06343298
- Phase 2
- Ages 18 to 80 years
- Sex: All
- Recruiting sites
- 22 US recruiting sites
- Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
NCT06402968
- Observational
- Ages 18 to 100 years
- Sex: All
- Recruiting sites
- 20 US recruiting sites
- An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.
NCT07543120
- Phase 2
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 19 US recruiting sites
- Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
NCT07090161
- Phase 2
- Ages 18 to 65 years
- Sex: All
- Recruiting sites
- 18 US recruiting sites
- BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
NCT06059638
- Interventional
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 16 US recruiting sites
- Recruiting sites
- 12 US recruiting sites
- A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
NCT07214376
- Interventional
- Ages 18 to 85 years
- Sex: All
- Recruiting sites
- 12 US recruiting sites
- Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension
NCT07511361
- Phase 2
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 12 US recruiting sites
- A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects
NCT06843577
- Interventional
- Ages 22 years and older
- Sex: All
- Recruiting sites
- 10 US recruiting sites
- Recruiting sites
- 8 US recruiting sites
- Improving Hypertension Control in Safety-Net Settings: The Boston Hypertension Equity Alliance in Treatment
NCT06948838
- Interventional
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 7 US recruiting sites
- Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension
NCT06526858
- Interventional
- Ages 22 to 80 years
- Sex: All
- Recruiting sites
- 6 US recruiting sites
- Optimizing Sustainable Cuff Access and Training Pathways for Self-Measured Blood Pressure Monitoring in Primary Care
NCT07693699
- Interventional
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 6 US recruiting sites
- Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404
- Observational
- Ages 0 to 20 years
- Sex: All
- Accepts healthy volunteers
- Recruiting sites
- 4 US recruiting sites
- Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
NCT06039176
- Observational
- Ages 18 to 100 years
- Sex: All
- Recruiting sites
- 4 US recruiting sites
- Neurovascular Transduction During Exercise in Chronic Kidney Disease
NCT02947750
- Phase 2
- Ages 18 to 75 years
- Sex: All
- Recruiting sites
- 3 US recruiting sites
- Technology-enabled Management Versus Usual Care for Blood Pressure
NCT05479461
- Interventional
- Ages 30 to 90 years
- Sex: All
- Recruiting sites
- 3 US recruiting sites
- Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia
NCT06281756
- Early Phase 1
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 3 US recruiting sites
- Recruiting sites
- 2 US recruiting sites
- Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US
NCT05129345
- Observational
- Ages 18 years and older
- Sex: All
- Accepts healthy volunteers
- Recruiting sites
- 2 US recruiting sites
- Recruiting sites
- 2 US recruiting sites
- Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults
NCT05955339
- Interventional
- Ages 18 years and older
- Sex: All
- Recruiting sites
- 2 US recruiting sites
FAQ
Common questions
What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a High Blood Pressure clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.