THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
NCT06559891
This study is recruiting at 34 US sites in 21 states, according to its ClinicalTrials.gov record last updated .
Summary
The primary objective of the THRIVE Pivotal study is to demonstrate the adjunctive effectiveness and the safety of the TIVUS system in: subjects with uncontrolled hypertension (HTN) receiving 0 - 2 anti-hypertensive drugs of different classes in whom the anti-hypertensive medications will be stopped for a 4-week wash-out period before RDN/Sham procedure and during 2 months after procedure.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Hypertension
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Not applicable
- Ages
- 22 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- SoniVie Inc.
- Last updated on ClinicalTrials.gov
- September 24, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- Cardiology, PC · Birmingham, AL
Arizona · 1
- HonorHealth · Scottsdale, AZ
Arkansas · 2
- St. Bernard's Medical Center · Jonesboro, AR
- Arkansas Heart Hospital · Little Rock, AR
California · 2
- Cedar-Sinai Medical Center · Los Angeles, CA
- Stanford University · Palo Alto, CA
Connecticut · 1
- Connecticut Clinical Research, LLC (Bridgeport) · Bridgeport, CT
Florida · 3
- Ascension- Sacred Heart · Pensacola, FL
- Baycare Health System · Safety Harbor, FL
- University of South Florida · Tampa, FL
Illinois · 3
- Ascension Alexian Brothers · Elk Grove Village, IL
- Southern Illinois University, School of Medicine · Springfield, IL
- St. John's Prairie Heart · Springfield, IL
Louisiana · 2
- Cardiovascular Institute of the South · Houma, LA
- Ochsner Medical Center · New Orleans, LA
Michigan · 2
- Henry Ford Hospital · Detroit, MI
- Henry Ford Providence Hospital · Southfield, MI
Mississippi · 2
- Gulfport Memorial Hospital · Gulfport, MS
- Jackson Heart Clinic · Jackson, MS
Missouri · 1
- St Lukes Hospital · Kansas City, MO
Nevada · 1
- Renown Regional Medical Center · Reno, NV
New Jersey · 2
- Virtua Health · Camden, NJ
- Jersey Shore University Medical Center · Neptune City, NJ
New York · 2
- St. Joseph · Liverpool, NY
- Nyph/Cumc · New York, NY
North Carolina · 1
- NC Heart and Vascular · Raleigh, NC
Oklahoma · 1
- Ascension St. John Clinical Research Institute · Bartlesville, OK
Pennsylvania · 2
- Lancaster General Health · Lancaster, PA
- Penn Medicine · Philadelphia, PA
South Carolina · 1
- MUSC · Mt. Pleasant, SC
Texas · 2
- Plaza Medical Center of Fort Worth · Fort Worth, TX
- Houston Medical Center · Houston, TX
Utah · 1
- St Marks Hospital · Salt Lake City, UT
Virginia · 1
- Chippenham Hospital · Richmond, VA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.