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Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension

NCT07511361

This study is recruiting at 12 US sites in 8 states, according to its ClinicalTrials.gov record last updated .

Summary

The purpose of this study is to evaluate the blood pressure-lowering effect of tonlamarsen in adult participants who were recently hospitalized and concurrently experienced an episode of acute severe hypertension.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Hypertension
  • Acute Severe Hypertension
  • Hypertensive Emergency
  • Hypertensive Urgency

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Kardigan, Inc.
Last updated on ClinicalTrials.gov
October 15, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Colorado · 1

  • Western Nephrology and Metabolic Bone Disease, PC - Arvada · Arvada, CO

Florida · 2

  • Homestead Associates in Research · Homestead, FL
  • Progressive Medical Research · Port Orange, FL

Illinois · 1

  • Eagle Clinical Research · Chicago, IL

Michigan · 1

  • Henry Ford Hospital · Detroit, MI

Ohio · 2

  • Research Innovations, LLC · Beavercreek, OH
  • Cleveland Clinic · Cleveland, OH

South Carolina · 1

  • OnSite Clinical Solutions, LLC · Fort Mill, SC

Tennessee · 1

  • Chattanooga Research & Medicine CHARM · Chattanooga, TN

Texas · 3

  • Laguna Clinical Research Associates · Laredo, TX
  • Tapia Internal Medicine Clinic · Paris, TX
  • Baylor Scott and White Research Institute - Temple · Temple, TX

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.