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Heart Failure Clinical Trials near Durham, NC

34 studies for Heart Failure are recruiting at 42 sites within 50 miles of Durham, North Carolina, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Heart Failure trials in the US or all trials near Durham.

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Heart Failure studies enrolling near Durham

Showing 34 studies, nearest first.
  1. Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

    NCT06736574

    • Phase 3
    • Ages 18 to 85 years
    • Sex: All

    Nearest sites: Duke University Hospital (Durham, NC); Clinical and Translational Research Center - University of North Carolina at Chapel Hill (Chapel Hill, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  2. Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

    NCT00271180

    • Observational
    • Ages Any age
    • Sex: All

    Nearest sites: (Durham, NC); (Raleigh, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  3. Alleviant ALLAY-HF Study

    NCT05685303

    • Interventional
    • Ages 40 years and older
    • Sex: All

    Nearest sites: Duke University Hospital (Durham, NC); NC Heart and Vascular Research (Raleigh, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  4. PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

    NCT05934487

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Duke University (Durham, NC); UNC Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  5. Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

    NCT06307652

    • Phase 3
    • Ages 18 to 130 years
    • Sex: All

    Nearest sites: Research Site (Durham, NC); Research Site (Chapel Hill, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  6. Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

    NCT06677060

    • Phase 3
    • Ages 40 years and older
    • Sex: All

    Nearest sites: Research Site (Durham, NC); Research Site (Raleigh, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  7. Alleviant ALLAY-HFrEF Study

    NCT06812533

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Duke University Hospital (Durham, NC); NC Heart and Vascular Research (Raleigh, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  8. Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

    NCT04278404

    • Observational
    • Ages 0 to 20 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Health System (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  9. Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

    NCT04592445

    • Interventional
    • Ages 40 years and older
    • Sex: All

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  10. Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment

    NCT05327062

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Duke University Hospital (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  11. A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

    NCT05489705

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Duke University Health System (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  12. Supporting Health in Veterans With Heart Failure

    NCT05839067

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: VA Clinic - Durham (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  13. Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction

    NCT06061549

    • Phase 1
    • Ages 50 years and older
    • Sex: All

    Nearest site: Duke University (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  14. Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

    NCT06080074

    • Phase 2
    • Ages 0 to 16 years
    • Sex: All

    Nearest site: Duke University Hospital (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  15. BiVACOR® Total Artificial Heart Early Feasibility Study

    NCT06174103

    • Interventional
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: Duke University Hospital (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

    NCT06310031

    • Interventional
    • Ages 18 to 100 years
    • Sex: All

    Nearest site: Duke University (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. ELEVATE-HFpEF Clinical Study

    NCT06678841

    • Interventional
    • Ages 40 years and older
    • Sex: All

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. Splanchnic X: Splanchnic Nerve Block in Heart Failure With Reduced Ejection Fraction

    NCT06733012

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Duke (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)

    NCT06895070

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

    NCT06898515

    • Interventional
    • Ages 22 years and older
    • Sex: All

    Nearest site: Duke University (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

    NCT06979362

    • Phase 2
    • Ages 40 to 84 years
    • Sex: All

    Nearest site: Duke University (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

    NCT07037459

    • Phase 3
    • Ages 18 to 99 years
    • Sex: All

    Nearest site: Duke University Health System (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

    NCT07069738

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. Eat Well Heart Failure

    NCT07101289

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Duke Health (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers

    NCT07159269

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke University Health System (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

    NCT07219511

    • Phase 1
    • Ages 50 years and older
    • Sex: All

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. Left vs Left Randomized Clinical Trial

    NCT05650658

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of North Carolina (Chapel Hill, NC)

    Distance to nearest recruiting site
    ~10 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. The EFfect of FinErenone in Kidney TransplantiOn Recipients: The EFFEKTOR Study

    NCT06059664

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: UNC Eastowne Kidney Transplant Clinic (Chapel Hill, NC)

    Distance to nearest recruiting site
    ~10 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

    NCT06526195

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of North Carolina at Chapel Hill (Chapel Hill, NC)

    Distance to nearest recruiting site
    ~10 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

    NCT06024746

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Morrisville, NC Investigative Site CON-10317 (Morrisville, NC)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

    NCT07567001

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Peak Clinical Trials (Apex, NC)

    Distance to nearest recruiting site
    ~18 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

    NCT06424288

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: WakeMed (Raleigh, NC)

    Distance to nearest recruiting site
    ~21 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

    NCT06425848

    • Observational
    • Ages 18 to 100 years
    • Sex: All

    Nearest site: University of North Carolina/ Rex Hospital, Inc. (Raleigh, NC)

    Distance to nearest recruiting site
    ~21 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

    NCT03142152

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Henrico Doctors Hospital (Henrico, VA)

    Distance to nearest recruiting site
    ~44 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Heart Failure clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.