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Depression Clinical Trials near New York, NY

105 studies for Depression are recruiting at 172 sites within 50 miles of New York, New York, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Depression trials in the US or all trials near New York.

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Depression studies enrolling near New York

Showing the 50 nearest of 105 studies.
  1. E-Mindfulness Approaches for Living After Breast Cancer

    NCT06748222

    • Phase 3
    • Ages 18 to 50 years
    • Sex: All

    Nearest sites: Mount Sinai Chelsea (New York, NY); Mount Sinai Hospital (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    18 sites within 50 mi
  2. Lay-Delivered Behavioral Activation in Senior Centers

    NCT04621877

    • Interventional
    • Ages 60 years and older
    • Sex: All

    Nearest sites: Carver Senior Center (New York, NY); Dyckman Senior Center (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  3. A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder

    NCT07573176

    • Phase 3
    • Ages 18 to 74 years
    • Sex: All

    Nearest sites: Adams Clinical Harlem (New York, NY); Fieve Clinical Research Inc (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    6 sites within 50 mi
  4. Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT06966401

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Neurocrine Clinical Site (New York, NY); Neurocrine Clinical Site (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  5. Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

    NCT07484217

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Clinical Research Site (New York, NY); Clinical Research Site (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  6. A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

    NCT06223880

    • Phase 4
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Clinical Research Site (New York, NY); Clinical Research Site (Brooklyn, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  7. Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

    NCT06559306

    • Phase 3
    • Ages 18 to 74 years
    • Sex: All

    Nearest sites: Fieve Clinical Research Inc (New York, NY); Integrative Clinical Trials LLC (Brooklyn, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  8. A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

    NCT07065240

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Seaport Investigator Site (New York, NY); Seaport Investigator Site (Brooklyn, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  9. Implementation of a Clinical Decision Support Tool for Postpartum Depression

    NCT06818734

    • Interventional
    • Ages 18 years and older
    • Sex: Female
    • Accepts healthy volunteers

    Nearest sites: Ob GYN Lower Manhattan 156 William street, New York City (New York, NY); Weill Cornell Medicine OBGYN practice 72 street (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  10. Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

    NCT06830044

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Vanda Investigational Site (New York, NY); Vanda Investigational Site (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  11. A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

    NCT03887715

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Icahn School of Medicine at Mount Sinai (New York, NY); ManuMind Interventional Psychiatry (Woodbury, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  12. Aβ Dynamics in LLMD

    NCT05004987

    • Phase 4
    • Ages 60 years and older
    • Sex: All

    Nearest sites: NYU Langone Health (New York, NY); Nathan S. Kline Institute for Psychiatric Research (Orangeburg, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  13. Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression - R33

    NCT05573074

    • Interventional
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: NYU Langone Health (New York, NY); Nathan Kline Institute for Psychiatric Research (Orangeburg, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  14. Triage Survey for Psychiatry Research Eligibility

    NCT05800925

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Adams Clinical, Harlem (New York, NY); Adams Clinical, Bronx (The Bronx, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  15. Harlem Strong Mental Health Coalition

    NCT05833555

    • Interventional
    • Ages 18 to 65 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: CUNY Graduate School of Public Health and Health Policy (New York, NY); Harlem Congregation for Community Improvement (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  16. Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

    NCT05850689

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Manhattan Behavioral Medicine (New York, NY); SPRI Clinical Trials, LLC (Brooklyn, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  17. Improving the Mental Health of Home Health Aides

    NCT06071221

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: 1199 SEIU Home Care Industry Education Fund (New York, NY); Weill Cornell Medicine (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  18. Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

    NCT06423430

    • Interventional
    • Ages 22 to 70 years
    • Sex: All

    Nearest sites: Mount Sinai Hospital (New York, NY); Robert Wood Johnson University Hospital (New Brunswick, NJ)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  19. A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

    NCT06524830

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: The Medical Research Network, LLC (New York, NY); Clinilabs, LLC (Eatontown, NJ)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  20. A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

    NCT06793397

    • Phase 3
    • Ages 18 to 85 years
    • Sex: All

    Nearest sites: Adams Clinical Harlem (New York, NY); Davis Clinical (Adams Clinical Bronx) (The Bronx, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  21. NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT06963021

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Neurocrine Clinical Site (New York, NY); Neurocrine Clinical Site (Cedarhurst, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  22. A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

    NCT07115329

    • Phase 2
    • Ages 18 to 64 years
    • Sex: All

    Nearest sites: IMA Clinical Research - NYC Midtown (New York, NY); IMA Clinical Research - NYC Uptown (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  23. A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder

    NCT07276997

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Ima Clinical Research - Manhattan /ID# 278212 (New York, NY); Manhattan Behavioral Medicine /ID# 277910 (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  24. A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

    NCT07610473

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest sites: Draig Clinical Site (New York, NY); Draig Clinical Site (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  25. A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression

    NCT07716098

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: The Medical Research Network, LLC (New York, NY); Neurobehavioral Research Inc (Cedarhurst, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  26. Biomarker-guided rTMS for Treatment Resistant Depression

    NCT04041479

    • Phase 3
    • Ages 22 to 65 years
    • Sex: All

    Nearest site: Weill Cornell Medicine (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. Virtual Reality for Pain Management in Burn Patients

    NCT04685486

    • Interventional
    • Ages 8 years and older
    • Sex: All

    Nearest site: Weill Cornell Medicine (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. Safe Mothers, Safe Children Initiative

    NCT04752618

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: McSilver Institute for Poverty Policy and Research (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. ROSE in Sunset Park

    NCT04940585

    • Interventional
    • Ages 18 to 100 years
    • Sex: Female
    • Accepts healthy volunteers

    Nearest site: NYU Langone Health (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. Telephone-Based Support Programs for People With Epilepsy

    NCT05082181

    • Interventional
    • Ages 18 to 99 years
    • Sex: All

    Nearest site: NYU Langone Health (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. Invasive Decoding and Stimulation of Altered Reward Computations in Depression Patients

    NCT05239780

    • Interventional
    • Ages 18 to 80 years
    • Sex: All

    Nearest site: Icahn School of Medicine at Mount Sinai (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. An Exploratory Study Examining Biopsychosocial Markers of Anxiety and Depression

    NCT05466851

    • Observational
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Singula Institute, 353 Lexington Avenue (Room 600) (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. A Digital Intervention for Post-Stroke Depression and Executive Dysfunction

    NCT05507138

    • Phase 2
    • Ages 50 to 79 years
    • Sex: All

    Nearest site: Weill Cornell Medical Center (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. Engage & Connect: A Psychotherapy for Postpartum Depression

    NCT05585164

    • Interventional
    • Ages Any age
    • Sex: Female

    Nearest site: Weill Cornell Medicine (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. Mindfulness-Based fMRI Neurofeedback for Depression

    NCT05617495

    • Interventional
    • Ages 13 to 18 years
    • Sex: All

    Nearest site: Columbia University Irving Medical Center (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. WeCare: A System of Care for Black Youth

    NCT05654207

    • Interventional
    • Ages 12 to 19 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Kings County Hospital (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  37. Personalized Mobile Cognitive Behavioral Therapy Application

    NCT05699525

    • Interventional
    • Ages 18 to 25 years
    • Sex: All

    Nearest site: Weill Cornell Medical College (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  38. Mobile CBT for Middle Aged and Older Adults

    NCT05754151

    • Interventional
    • Ages 40 years and older
    • Sex: All

    Nearest site: Weill Cornell Medicine (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  39. DBS for TRD With the Medtronic Percept PC

    NCT05773755

    • Interventional
    • Ages 25 to 70 years
    • Sex: All

    Nearest site: Icahn School of Medicine at Mount Sinai, Mount Sinai West (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  40. Brief Interventions for Coping with Distress

    NCT05779761

    • Interventional
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Teachers College, Columbia University (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  41. Feasibility and Acceptability of a Novel Cognitive Behavioral Skills Mobile App for Pregnant and Postpartum Individuals

    NCT05897619

    • Interventional
    • Ages 18 years and older
    • Sex: Female

    Nearest site: Weill Cornell Medical College (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide

    NCT05920252

    • Interventional
    • Ages 13 to 18 years
    • Sex: All

    Nearest site: Columbia University (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  43. Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality

    NCT05925322

    • Interventional
    • Ages 50 to 80 years
    • Sex: All

    Nearest site: Weill Cornell Medicine (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  44. Tele-PROTECT Therapy: Effectiveness, Empowerment, and Implementation

    NCT06039930

    • Interventional
    • Ages 60 years and older
    • Sex: All

    Nearest site: Weill Cornell Medicine (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  45. Neural Circuit Effects of Ketamine in Depression

    NCT06213324

    • Phase 4
    • Ages 18 to 65 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Icahn School of Medicine at Mount Sinai (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  46. Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients

    NCT06372964

    • Phase 3
    • Ages 10 to 17 years
    • Sex: All

    Nearest site: NYU Child Study Center (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  47. Heart Rate Variability (HRV)-Guided Transcranial Direct Current Stimulation (tDCS)

    NCT06455527

    • Interventional
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: NYU Langone Health (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  48. Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression

    NCT06559826

    • Phase 2
    • Ages 18 to 90 years
    • Sex: All

    Nearest site: Icahn School of Medicine at Mount Sinai (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  49. Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive Disorder

    NCT06592833

    • Phase 2
    • Ages 21 to 80 years
    • Sex: All

    Nearest site: Icahn School of Medicine at Mount Sinai, Center for Psychedelic Therapy Research (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  50. ALTO-100 in Bipolar Disorder With Depression (BD-D)

    NCT06656416

    • Phase 2
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: Site 6137 (New York, NY)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Depression clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.