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Study of ALTO-300 in MDD

NCT05922878

This study is recruiting at 37 US sites in 20 states, according to its ClinicalTrials.gov record last updated .

Summary

The purpose of this study is to determine efficacy differences between ALTO-300 and placebo, used adjunctively to an antidepressant, related to patient characteristics.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Major Depressive Disorder

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 to 70 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Alto Neuroscience
Last updated on ClinicalTrials.gov
July 24, 2025

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arizona · 2

  • Site 200 · Phoenix, AZ
  • Site 187 · Yuma, AZ

Arkansas · 1

  • Site 193 · Rogers, AR

California · 7

  • Site 218 · Bellflower, CA
  • Site 217 · Glendale, CA
  • Site 335 · Lafayette, CA
  • Site 209 · Los Angeles, CA
  • Site 219 · Mather, CA
  • Site 194 · Mission Viejo, CA
  • Site 197 · Temecula, CA

Colorado · 2

  • Site 203 · Colorado Springs, CO
  • Site 349 · Evergreen, CO

Connecticut · 1

  • Site 214 · Norwalk, CT

Florida · 6

  • Site 159 · Clermont, FL
  • Site 225 · Miami Gardens, FL
  • Site 190 · Miami Lakes, FL
  • Site 161 · Okeechobee, FL
  • Site 221 · Tampa, FL
  • Site 220 · West Palm Beach, FL

Georgia · 2

  • Site 224 · Savannah, GA
  • Site 208 · Snellville, GA

Idaho · 1

  • Site 119 · Boise, ID

Illinois · 1

  • Site 310 · Chicago, IL

Mississippi · 1

  • Site 215 · Jackson, MS

Nevada · 1

  • Site 344 · Las Vegas, NV

New Mexico · 1

  • Site 114 · Albuquerque, NM

New York · 1

  • Site 192 · Staten Island, NY

North Carolina · 1

  • Site 199 · Hickory, NC

Ohio · 1

  • Site 202 · Cincinnati, OH

Oklahoma · 1

  • Site 195 · Oklahoma City, OK

Pennsylvania · 3

  • Site 216 · Allentown, PA
  • Site 350 · Media, PA
  • Site 352 · Moosic, PA

Texas · 2

  • Site 347 · Fort Worth, TX
  • Site 196 · Richmond, TX

Utah · 1

  • Site 207 · Clinton, UT

Virginia · 1

  • Site 211 · Roanoke, VA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.