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Double-blind, Placebo-controlled Study in Adults With Major Depressive Disorder

NCT07226661

This study is recruiting at 40 US sites in 20 states, according to its ClinicalTrials.gov record last updated .

Summary

This study will evaluate the efficacy and safety of SPN-821 in adults with major depressive disorder

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Major Depressive Disorder (MDD)

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 to 70 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Supernus Pharmaceuticals, Inc.
Last updated on ClinicalTrials.gov
October 28, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Alabama · 1

  • University of Alabama · Birmingham, AL

Arizona · 1

  • IMA Clinical Research Phoenix · Phoenix, AZ

Arkansas · 1

  • Woodland Research Northwest (ERG) · Rogers, AR

California · 9

  • Inland Psychiatric Medical Group · Chino, CA
  • Leading Edge Research (Eximia Network) · Encino, CA
  • Cenexel Collaborative Neuroscience Network · Garden Grove, CA
  • Synergy Research (ERG Network) · Lemon Grove, CA
  • Catalina Research Institute (Elixia) · Montclair, CA
  • ATP Clinical Research · Orange, CA
  • NRC Research Institute · Orange, CA
  • Lumos Clinical Research Center · San Jose, CA
  • Inland Psychiatric Medical Group · Temecula, CA

Colorado · 1

  • Mountain View Clinical Research · Denver, CO

Connecticut · 1

  • CT Clinical Research · Cromwell, CT

Florida · 6

  • CNS Healthcare - Jacksonville · Jacksonville, FL
  • Avantis Clinical Research · Miami, FL
  • CNS Healthcare of Orlando · Orlando, FL
  • Space Coast Neuropsychiatric Research Institute · Palm Bay, FL
  • Cenexel Tampa · Tampa, FL
  • Interventional Psychiatry of Tampa Bay · Tampa, FL

Georgia · 2

  • Cenexel Atlanta (ACMR) · Atlanta, GA
  • Cenexel iResearch Atlanta · Decatur, GA

Illinois · 1

  • AMR Conventions Research · Warrenville, IL

Mississippi · 1

  • Precise Clinical Research · Flowood, MS

Missouri · 2

  • Psychiatric Care and Research Center · O'Fallon, MO
  • Midwest Research Group · Saint Charles, MO

Nevada · 1

  • Vector Clinical Trials · Las Vegas, NV

New Jersey · 1

  • Cenexel Marlton (HRI) · Marlton, NJ

New York · 2

  • SPRI Clinical Trials · Brooklyn, NY
  • Manhattan Behavioral Medicine · New York, NY

North Carolina · 1

  • New Hope Clinical Research · Charlotte, NC

Oklahoma · 1

  • Paradigm Research Professionals · Oklahoma City, OK

Oregon · 1

  • Summit Headlands (Headlands Research) · Portland, OR

Texas · 4

  • Houston Clinical Trials · Bellaire, TX
  • Baylor College of Medicine · Houston, TX
  • DM Clinical · Houston, TX
  • Grayline Research Center · Wichita Falls, TX

Utah · 2

  • Alpine Research Organization · Clinton, UT
  • Aura Wellness · Salt Lake City, UT

Washington · 1

  • Core Clinical Research · Everett, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.