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Rheumatoid Arthritis Clinical Trials Recruiting in the US

62 studies for Rheumatoid Arthritis are recruiting at 421 US sites, according to ClinicalTrials.gov data processed .

Rheumatoid arthritis is a long-term autoimmune disease that mainly causes inflammation, pain and swelling in the joints.

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Recruiting now

Top Rheumatoid Arthritis studies by number of US sites

Showing 30 studies, most US recruiting sites first.
  1. A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

    NCT06972446

    • Phase 2
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    49 US recruiting sites
  2. RA-PRO PRAGMATIC TRIAL

    NCT04692493

    • Phase 3
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    48 US recruiting sites
  3. Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

    NCT03816345

    • Phase 1
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    40 US recruiting sites
  4. AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

    NCT06991114

    • Phase 2
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    31 US recruiting sites
  5. Exactech Shoulder Post Market Clinical Follow-up Study

    NCT05603728

    • Observational
    • Ages 21 years and older
    • Sex: All
    Recruiting sites
    24 US recruiting sites
  6. A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis

    NCT07276581

    • Phase 2
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    22 US recruiting sites
  7. A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)

    NCT07409103

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    22 US recruiting sites
  8. A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)

    NCT07137598

    • Phase 2
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    17 US recruiting sites
  9. A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

    NCT06733935

    • Phase 1/2
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    15 US recruiting sites
  10. A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

    NCT06570798

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    13 US recruiting sites
  11. Phase 1b/2 Study of IV Sarilumab in Adult With RA

    NCT07704580

    • Phase 1/2
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    12 US recruiting sites
  12. A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions and Subcutaneous Injections of ABBV-519 in Adult Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)

    NCT07607964

    • Phase 1
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    11 US recruiting sites
  13. ConsideRAte Study - Splenic Stimulation for RA

    NCT05003310

    • Interventional
    • Ages 22 to 75 years
    • Sex: All
    Recruiting sites
    10 US recruiting sites
  14. Study of Single Doses of SBT777101 in Subjects With Rheumatoid Arthritis

    NCT06201416

    • Phase 1
    • Ages 18 to 70 years
    • Sex: All
    Recruiting sites
    9 US recruiting sites
  15. A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis

    NCT07258849

    • Phase 1
    • Ages 18 to 75 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    9 US recruiting sites
  16. A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeutic

    NCT07123038

    • Observational
    • Ages 18 to 71 years
    • Sex: All
    Recruiting sites
    7 US recruiting sites
  17. Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA

    NCT07237659

    • Phase 1
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    7 US recruiting sites
  18. R-2487 in Patients With Rheumatoid Arthritis

    NCT05961592

    • Phase 1
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    6 US recruiting sites
  19. Clinical Outcomes Study of the Nexel Total Elbow

    NCT02469662

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    4 US recruiting sites
  20. Defining the Molecular and Radiologic Phenotype of Progressive RA Interstitial Lung Disease

    NCT06397677

    • Observational
    • Ages 18 to 90 years
    • Sex: All
    Recruiting sites
    4 US recruiting sites
  21. An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants With Rheumatoid Arthritis

    NCT07620392

    • Phase 2
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    4 US recruiting sites
  22. Physica System Total Knee Replacement Registry Study

    NCT03048201

    • Interventional
    • Ages 22 years and older
    • Sex: All
    Recruiting sites
    3 US recruiting sites
  23. A Dose Response Study to Evaluate the Efficacy and Safety of Oral AP1189 Administered in Disease-Modifying Anti-Rheumatic Drug (DMARD) naïve Participants Participants With Early Rheumatoid Arthritis

    NCT06671054

    • Phase 2
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    3 US recruiting sites
  24. Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants

    NCT07201558

    • Phase 1
    • Ages 18 to 65 years
    • Sex: All
    Recruiting sites
    3 US recruiting sites
  25. Ultrasound Neuroimmune Modulation in Adults With Rheumatoid Arthritis

    NCT07293871

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    3 US recruiting sites
  26. The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

    NCT07315997

    • Observational
    • Ages 35 to 79 years
    • Sex: All
    Recruiting sites
    3 US recruiting sites
  27. Exactech Vantage Total Ankle System Post Market Clinical Follow-Up - US Only

    NCT05619588

    • Observational
    • Ages 21 years and older
    • Sex: All
    Recruiting sites
    2 US recruiting sites
  28. Dynamic Treatment Regiments for Glucocorticoid Tapering

    NCT06072768

    • Phase 2
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    2 US recruiting sites
  29. EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))

    NCT06631638

    • Interventional
    • Ages 21 years and older
    • Sex: All
    Recruiting sites
    2 US recruiting sites
  30. A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.

    NCT06916806

    • Phase 1
    • Ages 18 to 70 years
    • Sex: All
    Recruiting sites
    2 US recruiting sites

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Rheumatoid Arthritis clinical trials by city

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Rheumatoid Arthritis clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.