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A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

NCT06972446

This study is recruiting at 49 US sites in 17 states, according to its ClinicalTrials.gov record last updated .

Summary

Rheumatoid Arthritis (RA) is a chronic inflammatory disease causing pain, stiffness, swelling and loss of joint function. This study will evaluate the efficacy and safety of targeted therapies through a series of substudies for the treatment of moderately to severely active Rheumatoid Arthritis (RA). This study currently includes 3 substudies evaluating different treatments in participants with RA. Substudy 1 will evaluate lutikizumab monotherapy (treatment given alone) compared to placebo (looks like the study treatment but contains no medicine).

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Rheumatoid Arthritis

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
AbbVie
Last updated on ClinicalTrials.gov
October 8, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arizona · 1

  • Sun Valley Arthritis Center /ID# 278331 · Peoria, AZ

Arkansas · 1

  • Arthritis And Rheumatism Associates (Ara) - Jonesboro /ID# 272896 · Jonesboro, AR

California · 6

  • Private Practice - Dr. David S. Hallegua /ID# 277608 · Beverly Hills, CA
  • Advanced Clinical Research Center, LLC dba TriWest Research Associates /ID# 277826 · Chula Vista, CA
  • Newport Huntington Medical Group /ID# 272439 · Huntington Beach, CA
  • Cohen Medical Centers /ID# 278341 · Thousand Oaks, CA
  • The Lundquist Institute /ID# 272481 · Torrance, CA
  • Inland Rheumatology and Osteoporosis Medical Group /ID# 272449 · Upland, CA

Colorado · 1

  • Tekton Research - Fort Collins - East Harmony Road /ID# 272472 · Fort Collins, CO

Florida · 10

  • Highlands Advanced Rheumatology And Arthritis Center - Avon Park /ID# 272298 · Avon Park, FL
  • Clinical Research Of West Florida - Phase I Unit /ID# 272428 · Clearwater, FL
  • Finlay Medical Research - Greenacres /ID# 281654 · Greenacres City, FL
  • Neoclinical Research - Hialeah /ID# 272070 · Hialeah, FL
  • South Florida Rheumatology /ID# 278339 · Hollywood, FL
  • Swati Shah, MD Rheumatology /ID# 273624 · Jacksonville, FL
  • Life Clinical Trials - Colonial Drive - Margate /ID# 272589 · Margate, FL
  • HMD Research LLC /ID# 272432 · Orlando, FL
  • Vitalia Research /ID# 272478 · Palm Beach Gardens, FL
  • Clinical Research Of West Florida - Tampa - North Howard Avenue /ID# 272755 · Tampa, FL

Illinois · 5

  • Northwestern Medicine - Northwestern Memorial Hospital /ID# 275422 · Chicago, IL
  • Deerbrook Medical Associates /ID# 273439 · Libertyville, IL
  • Advanced Quality Medical Research /ID# 277824 · Orland Park, IL
  • Arnold Arthritis & Rheumatology /ID# 278354 · Skokie, IL
  • Willow Rheumatology and Wellness /ID# 272691 · Willowbrook, IL

Louisiana · 1

  • Accurate Clinical Research (SMO/Network/Consortium) /ID# 272650 · Lake Charles, LA

Michigan · 1

  • AA Medical Research Center - Grand Blanc /ID# 272496 · Grand Blanc, MI

New Jersey · 1

  • Sahni Rheumatology & Therapy /ID# 278352 · West Long Branch, NJ

New Mexico · 1

  • Albuquerque Center For Rheumatology /ID# 272301 · Albuquerque, NM

New York · 1

  • Northwell Health Physician Partners Rheumatology At Great Neck /ID# 275621 · Great Neck, NY

North Carolina · 2

  • DJL Clinical Research - Charlotte /ID# 272387 · Charlotte, NC
  • Joint And Muscle Research Institute /ID# 277290 · Charlotte, NC

Ohio · 1

  • Paramount Medical Research and Consulting /ID# 272474 · Middleburg Heights, OH

Pennsylvania · 1

  • Altoona Center For Clinical Research /ID# 272479 · Duncansville, PA

South Carolina · 1

  • Low Country Rheumatology /ID# 277607 · Summerville, SC

Tennessee · 1

  • West Tennessee Research Institute /ID# 272453 · Jackson, TN

Texas · 14

  • Tekton Research - West Gate /ID# 272270 · Austin, TX
  • Trinity Universal Research Associates - Carrollton /ID# 272577 · Carrollton, TX
  • Arthritis Care Of Texas /ID# 277961 · Corpus Christi, TX
  • Arthritis and Rheumatology Research Institute - Frisco /ID# 272299 · Frisco, TX
  • Accurate Clinical Research - Houston /ID# 272271 · Houston, TX
  • Care & Cure Clinic /ID# 281684 · Houston, TX
  • Private Practice - Dr. Laila A. Hassan /ID# 272297 · Houston, TX
  • Biopharma Informatic /ID# 279189 · Katy, TX
  • Southwest Rheumatology Research /ID# 272268 · Mesquite, TX
  • Texas Rheumatology Research Institute /ID# 278010 · Plano, TX
  • Epic Medical Research /ID# 272656 · Red Oak, TX
  • Fort Bend Rheumatology Associates /ID# 280761 · Sugar Land, TX
  • DM Clinical Research - Tomball /ID# 272452 · Tomball, TX
  • Dm Clinical Research -Tomball Rch /ID# 281787 · Tomball, TX

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.