Skip to content
Trial Eligibility
Menu

Depression Clinical Trials near San Francisco, CA

48 studies for Depression are recruiting at 71 sites within 50 miles of San Francisco, California, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Depression trials in the US or all trials near San Francisco.

Your ZIP is looked up in your browser. We don't receive or store it.

Recruiting now

Depression studies enrolling near San Francisco

Showing 48 studies, nearest first.
  1. E-Mindfulness Approaches for Living After Breast Cancer

    NCT06748222

    • Phase 3
    • Ages 18 to 50 years
    • Sex: All

    Nearest sites: Kaiser Permanente-San Francisco (San Francisco, CA); Kaiser Permanente-South San Francisco (South San Francisco, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    19 sites within 50 mi
  2. A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations

    NCT06367764

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: UCSF Alliance Health Project (San Francisco, CA); Stanford University (Palo Alto, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  3. Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT06966401

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Neurocrine Clinical Site (San Francisco, CA); Neurocrine Clinical Site (San Jose, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  4. A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

    NCT07115329

    • Phase 2
    • Ages 18 to 64 years
    • Sex: All

    Nearest sites: Studyops Inc (San Francisco, CA); Lumos Clinical Research Center (San Jose, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  5. Characterizing Cognitive Decline in Late Life Depression: The ADNI Depression Project

    NCT02434393

    • Observational
    • Ages 65 years and older
    • Sex: All

    Nearest site: University of California, San Francisco (San Francisco, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  6. Closed-Loop Deep Brain Stimulation for Major Depression

    NCT04004169

    • Interventional
    • Ages 22 to 70 years
    • Sex: All

    Nearest site: University of California, San Francisco (San Francisco, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  7. Near Infrared Spectroscopy (NIRS) for Assessment of Depression

    NCT04061148

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: San Francisco Veterans Affairs Medical Center (San Francisco, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  8. Biomarkers of Depression and Treatment Response

    NCT04581902

    • Interventional
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: University of California, San Francisco (San Francisco, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  9. Model-based Electrical Brain Stimulation

    NCT05327387

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of California, San Francisco (San Francisco, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  10. Treating Major Depression With Yoga Mono-therapy

    NCT06091527

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Zuckerberg San Francisco General Hospital (San Francisco, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  11. Ketamine for Veterans With Parkinson's Disease

    NCT06231563

    • Phase 2
    • Ages 40 to 80 years
    • Sex: All

    Nearest site: San Francisco VA Medical Center, San Francisco, CA (San Francisco, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  12. Psilocybin Therapy for Depression in Parkinson's Disease

    NCT06455293

    • Phase 2
    • Ages 40 to 80 years
    • Sex: All

    Nearest site: University of California, San Francisco (San Francisco, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  13. Probiotic Administration for Adolescent Depression

    NCT06898788

    • Early Phase 1
    • Ages 15 to 24 years
    • Sex: All

    Nearest site: UCSF (San Francisco, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  14. NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT06911112

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Neurocrine Clinical Site (San Francisco, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  15. Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression

    NCT07127913

    • Interventional
    • Ages 22 to 70 years
    • Sex: All

    Nearest site: University of California, San Francisco (San Francisco, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. SUpport From PEeRs to Expand Access Study - Community

    NCT07186816

    • Interventional
    • Ages 18 to 100 years
    • Sex: All

    Nearest site: Zuckerberg San Francisco General (San Francisco, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder

    NCT07775300

    • Phase 3
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: Oakland Clinical (Oakland, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. Study of ALTO-300 in MDD

    NCT05922878

    • Phase 2
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: Site 335 (Lafayette, CA)

    Distance to nearest recruiting site
    ~18 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

    NCT06223880

    • Phase 4
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Clinical Research Site (Lafayette, CA)

    Distance to nearest recruiting site
    ~18 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

    NCT07610473

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: Draig Clinical Site (Lafayette, CA)

    Distance to nearest recruiting site
    ~18 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)

    NCT06633016

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Autobahn Site #126 (Walnut Creek, CA); Autobahn Site #119 (San Jose, CA)

    Distance to nearest recruiting site
    ~21 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  22. Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

    NCT06830044

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Vanda Investigational Site (Walnut Creek, CA); Vanda Investigational Site (San Jose, CA)

    Distance to nearest recruiting site
    ~21 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  23. Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

    NCT06547489

    • Phase 2
    • Ages 18 to 64 years
    • Sex: All

    Nearest site: Sunwise Clinical Research LLC (Walnut Creek, CA)

    Distance to nearest recruiting site
    ~21 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder

    NCT07276997

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Sunwise Clinical Research /ID# 277555 (Walnut Creek, CA)

    Distance to nearest recruiting site
    ~21 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

    NCT07484217

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Clinical Research Site (Walnut Creek, CA)

    Distance to nearest recruiting site
    ~21 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder

    NCT07573176

    • Phase 3
    • Ages 18 to 74 years
    • Sex: All

    Nearest site: Sunwise Clinical Research (Walnut Creek, CA)

    Distance to nearest recruiting site
    ~21 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

    NCT07621237

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Sunwise Clinical Research, Llc (Walnut Creek, CA)

    Distance to nearest recruiting site
    ~21 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. Brexanolone Lifting Outcomes Of Moms

    NCT07822321

    • Phase 3
    • Ages 15 to 45 years
    • Sex: Female

    Nearest site: Lipocine Investigational Site (Walnut Creek, CA)

    Distance to nearest recruiting site
    ~21 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. rTMS for Military TBI-related Depression

    NCT05426967

    • Interventional
    • Ages 18 to 55 years
    • Sex: All

    Nearest site: VA Palo Alto Health Care System (Palo Alto, CA)

    Distance to nearest recruiting site
    ~28 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. Sleep Mechanisms Of Regulating Emotions

    NCT06373718

    • Interventional
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Stanford University (Palo Alto, CA)

    Distance to nearest recruiting site
    ~28 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. ACE-D Aim 3 Clinical Cognitive Trial to Enhance Translation in Depression

    NCT06408246

    • Phase 2
    • Ages 18 to 60 years
    • Sex: All

    Nearest site: Stanford Psychiatry and Behavioral Sciences Department (Palo Alto, CA)

    Distance to nearest recruiting site
    ~28 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. Stratified Pharmacological Approaches for Regulating Circuit-Level Effects

    NCT07022405

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Stanford University (Palo Alto, CA)

    Distance to nearest recruiting site
    ~28 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. Biomarker-guided rTMS for Treatment Resistant Depression

    NCT04041479

    • Phase 3
    • Ages 22 to 65 years
    • Sex: All

    Nearest site: Stanford University (Stanford, CA)

    Distance to nearest recruiting site
    ~28 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. Treatment of Acute Mood Depressive Episode in Borderline Personality Disorder With rTMS

    NCT04870255

    • Interventional
    • Ages 18 to 80 years
    • Sex: All

    Nearest site: Stanford Hospital (Stanford, CA)

    Distance to nearest recruiting site
    ~28 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. Investigating the Neural Mechanisms of Repetitive Brain Stimulation With Invasive and Noninvasive Electrophysiology in Humans

    NCT05996900

    • Interventional
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Stanford University (Stanford, CA)

    Distance to nearest recruiting site
    ~28 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. fMRI Neurofeedback With Matter Neuroscience App

    NCT06735885

    • Interventional
    • Ages 18 to 80 years
    • Sex: All

    Nearest site: Stanford University Brain Stimulation Lab (Stanford, CA)

    Distance to nearest recruiting site
    ~28 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  37. Sleep TMS for Depression

    NCT06824415

    • Interventional
    • Ages 18 to 65 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Stanford University (Stanford, CA)

    Distance to nearest recruiting site
    ~28 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  38. NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT06963021

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Neurocrine Clinical Site (Stanford, CA)

    Distance to nearest recruiting site
    ~28 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  39. Phase II: Engagement and Clinical Impact of the Teleo Virtual Therapy Platform in Clinical Settings

    NCT07155707

    • Interventional
    • Ages 5 to 14 years
    • Sex: All

    Nearest site: Stanford University (Stanford, CA)

    Distance to nearest recruiting site
    ~28 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  40. Virtual Reality-Enhanced Behavioral Activation for Older Adults With Depression

    NCT07188623

    • Interventional
    • Ages 65 years and older
    • Sex: All

    Nearest site: Stanford University (Stanford, CA)

    Distance to nearest recruiting site
    ~28 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  41. Optimizing Brain Excitability in Depression

    NCT07242105

    • Interventional
    • Ages 18 to 65 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Stanford University (Stanford, CA)

    Distance to nearest recruiting site
    ~28 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. The BEAR Program for Women With Trauma Who Have Suicidal Thoughts

    NCT07346638

    • Interventional
    • Ages 18 to 75 years
    • Sex: Female

    Nearest site: Stanford University School of Medicine (Stanford, CA)

    Distance to nearest recruiting site
    ~28 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  43. Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

    NCT06376734

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Acacia Clinics (Sunnyvale, CA)

    Distance to nearest recruiting site
    ~35 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  44. Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

    NCT06559306

    • Phase 3
    • Ages 18 to 74 years
    • Sex: All

    Nearest site: Lumos Clinical Research Center LLC (San Jose, CA)

    Distance to nearest recruiting site
    ~42 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  45. ALTO-100 in Bipolar Disorder With Depression (BD-D)

    NCT06656416

    • Phase 2
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: Site 6120 (San Jose, CA)

    Distance to nearest recruiting site
    ~42 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  46. A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

    NCT07065240

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Seaport Investigator Site (San Jose, CA)

    Distance to nearest recruiting site
    ~42 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  47. A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT07196501

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Neurocrine Clinical Site (San Jose, CA)

    Distance to nearest recruiting site
    ~42 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  48. RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

    NCT07002034

    • Phase 2
    • Ages 18 to 80 years
    • Sex: All

    Nearest site: Providence Medical Foundation (Santa Rosa, CA)

    Distance to nearest recruiting site
    ~49 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Depression clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.