ALTO-207 in Adults With Treatment-resistant Depression (TRD)
NCT07553637
This study is recruiting at 40 US sites in 18 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this trial is to measure depressive symptoms following treatment with ALTO-207 compared with placebo in participants with TRD.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Treatment-resistant Depression (TRD)
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Alto Neuroscience
- Last updated on ClinicalTrials.gov
- October 26, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- Site 7173 · Dothan, AL
Arizona · 1
- Site 7000 · Phoenix, AZ
California · 8
- Site 7153 · Chino, CA
- Site 7069 · Los Angeles, CA
- Site 7156 · Oakland, CA
- Site 7082 · Oceanside, CA
- Site 7016 · Sacramento, CA
- Site 7144 · San Diego, CA
- Site 7120 · San Jose, CA
- Site 7171 · Valley Village, CA
Florida · 1
- Site 7152 · Saint Augustine, FL
Georgia · 4
- Site 7148 · Albany, GA
- Site 7146 · Marietta, GA
- Site 7141 · Savannah, GA
- Site 7064 · Snellville, GA
Illinois · 1
- Site 7192 · Naperville, IL
Indiana · 1
- Site 7169 · Indianapolis, IN
Maryland · 2
- Site 7054 · Pikesville, MD
- Site 7180 · Rockville, MD
Massachusetts · 1
- Site 7166 · Worcester, MA
Michigan · 2
- Site 7155 · Ann Arbor, MI
- Site 7154 · Bloomfield Hills, MI
Missouri · 1
- Site 7189 · St Louis, MO
New Jersey · 1
- Site 7066 · Toms River, NJ
New York · 4
- Site 7170 · Amherst, NY
- Site 7055 · Cedarhurst, NY
- Site 7162 · Lewiston, NY
- Site 7157 · Syracuse, NY
North Carolina · 2
- Site 7127 · Cary, NC
- Site 7143 · Charlotte, NC
Ohio · 2
- Site 7029 · Cincinnati, OH
- Site 7158 · Garfield Heights, OH
Rhode Island · 1
- Site 7172 · East Providence, RI
Texas · 6
- Site 7176 · Dallas, TX
- Site 7160 · Fort Worth, TX
- Site 7145 · Houston, TX
- Site 7175 · Houston, TX
- Site 7161 · Irving, TX
- Site 7186 · Plano, TX
Virginia · 1
- Site 7177 · Fairfax, VA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.