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Depression Clinical Trials near San Diego, CA

36 studies for Depression are recruiting at 44 sites within 50 miles of San Diego, California, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Depression trials in the US or all trials near San Diego.

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Recruiting now

Depression studies enrolling near San Diego

Showing 36 studies, nearest first.
  1. A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

    NCT06223880

    • Phase 4
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Clinical Research Site (San Diego, CA); Clinical Research Site (Oceanside, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  2. E-Mindfulness Approaches for Living After Breast Cancer

    NCT06748222

    • Phase 3
    • Ages 18 to 50 years
    • Sex: All

    Nearest sites: Kaiser Permanente-San Diego Zion (San Diego, CA); Kaiser Permanente-San Marcos (San Marcos, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  3. Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT06966401

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Neurocrine Clinical Site (San Diego, CA); Neurocrine Clinical Site (Oceanside, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  4. A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression

    NCT07300969

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest sites: Draig Clinical Site (San Diego, CA); Draig Clinical Site (Oceanside, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  5. Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

    NCT07484217

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Clinical Research Site (San Diego, CA); Clinical Research Site (Oceanside, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  6. ALTO-207 in Adults With Treatment-resistant Depression (TRD)

    NCT07553637

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest sites: Site 7144 (San Diego, CA); Site 7082 (Oceanside, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  7. A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

    NCT07621237

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Artemis Institute For Clinical Research - San Diego (San Diego, CA); Synergy Research - San Diego (Lemon Grove, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  8. An Online Intuitive Eating Program for Pregnant Women With Obesity to Support Well-Being

    NCT07792837

    • Interventional
    • Ages 18 years and older
    • Sex: Female

    Nearest sites: San Diego State University (San Diego, CA); UC San Diego Health (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  9. Combined Transcranial Magnetic Stimulation and Therapy for MTBI Related Headaches

    NCT05176392

    • Interventional
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: VA San Diego Healthcare System (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  10. Cortical Inhibition as a Biomarker of Response in a Comparison of Bilateral Versus Unilateral Accelerated Theta Burst Stimulation for Suicidal Ideation in Treatment-Resistant Depression -COMBAT-SI

    NCT05377177

    • Interventional
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: UCSD Interventional Psychiatry (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  11. Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans

    NCT06162741

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: VA San Diego Healthcare System, San Diego, CA (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  12. Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)

    NCT06273527

    • Phase 2/3
    • Ages 21 to 55 years
    • Sex: All

    Nearest site: UC San Diego (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  13. Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction

    NCT06678880

    • Interventional
    • Ages 45 to 75 years
    • Sex: Female

    Nearest site: University of California San Diego Hillcrest Medical Center (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  14. Be Well at Work-Plus: A Depression and Physical Activity Intervention for Hospital Service Workers (Aim 2)

    NCT06753123

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: San Diego State University (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  15. Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT06786624

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Neurocrine Clinical Site (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. Maintenance rTMS for Depression (Maitr-De)

    NCT06938841

    • Interventional
    • Ages 18 to 80 years
    • Sex: All

    Nearest site: University of California, San Diego (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

    NCT07002034

    • Phase 2
    • Ages 18 to 80 years
    • Sex: All

    Nearest site: Kadima Neuropsychiatry Institute (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

    NCT07105111

    • Phase 4
    • Ages 18 years and older
    • Sex: All

    Nearest site: Neurocrine Clinical Site (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety Study

    NCT07217223

    • Interventional
    • Ages 18 to 85 years
    • Sex: All

    Nearest site: UCSD Interventional Psychiatry (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. Sleep Health in U.S. Marines

    NCT07420205

    • Phase 2
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: San Diego State University (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. Mindfulness Engaged Neurostimulation for Depression (MEND II)

    NCT07512284

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: UC San Diego Health Psychiatry (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

    NCT07592689

    • Phase 3
    • Ages 18 to 74 years
    • Sex: All

    Nearest site: Kadima Neuropsychiatry Institute (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression

    NCT07716098

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Artemis Institute for Clinical Research (San Diego, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder

    NCT07276997

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Synergy San Diego /ID# 277553 (Lemon Grove, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

    NCT03887715

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Kaizen Brain Center (La Jolla, CA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. Combined Neuromodulation and Cognitive Training for Post-mTBI Depression

    NCT05682677

    • Interventional
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: UCSD (La Jolla, CA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

    NCT06524830

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Kadima Neuropsychiatry Institute (La Jolla, CA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. Meditative Neurofeedback for Depression

    NCT06675240

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of California San Diego (La Jolla, CA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial

    NCT07223736

    • Interventional
    • Ages 18 years and older
    • Sex: Female

    Nearest site: University of California San Diego (La Jolla, CA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

    NCT07284667

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Kadima Neuropsychiatry Institute (La Jolla, CA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. Nutritional Intervention for College Students With Depression

    NCT07490782

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: University of California San Diego (La Jolla, CA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1

    NCT07528014

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Salma Health (La Jolla, CA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

    NCT06559306

    • Phase 3
    • Ages 18 to 74 years
    • Sex: All

    Nearest site: Excell Research Inc (Oceanside, CA)

    Distance to nearest recruiting site
    ~35 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

    NCT07115329

    • Phase 2
    • Ages 18 to 64 years
    • Sex: All

    Nearest site: Excell Research, Inc (Oceanside, CA)

    Distance to nearest recruiting site
    ~35 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT07196501

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Neurocrine Clinical Site (Oceanside, CA)

    Distance to nearest recruiting site
    ~35 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder

    NCT07573176

    • Phase 3
    • Ages 18 to 74 years
    • Sex: All

    Nearest site: Excell Research Inc (Oceanside, CA)

    Distance to nearest recruiting site
    ~35 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Depression clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.