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Depression Clinical Trials near Orlando, FL

26 studies for Depression are recruiting at 37 sites within 50 miles of Orlando, Florida, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Depression trials in the US or all trials near Orlando.

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Recruiting now

Depression studies enrolling near Orlando

Showing 26 studies, nearest first.
  1. A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

    NCT06223880

    • Phase 4
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Clinical Research Site (Orlando, FL); Clinical Research Site (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  2. A Study of Brenipatide in Adult Participants With Major Depressive Disorder

    NCT07412756

    • Phase 3
    • Ages 18 to 75 years
    • Sex: All

    Nearest sites: Charter Research - Orlando (Orlando, FL); K2 Medical Research - Maitland (Maitland, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  3. A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

    NCT07621237

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Clinical Neuroscience Solutions Inc. - Orlando (Orlando, FL); K2 Medical Research - Maitland (Maitland, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  4. A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

    NCT03887715

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: APG Research, LLC (Orlando, FL); Nova Psychiatry Inc. (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  5. A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

    NCT04777357

    • Phase 3
    • Ages 10 to 17 years
    • Sex: All

    Nearest sites: Nova Psychiatry Inc. /ID# 270892 (Orlando, FL); Medical Research Group of Central Florida /ID# 256757 (Orange City, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  6. A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

    NCT07592689

    • Phase 3
    • Ages 18 to 74 years
    • Sex: All

    Nearest sites: Clinical Neuroscience Solutions, LLC (Orlando) (Orlando, FL); K2 Medical Research (Maitland) (Maitland, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  7. A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

    NCT07610473

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest sites: Draig Clinical Site (Orlando, FL); Draig Clinical Site (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  8. The Lake Nona Life Project

    NCT02533804

    • Observational
    • Ages 18 to 110 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Lake Nona Institute (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  9. Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics

    NCT05877885

    • Interventional
    • Ages 60 years and older
    • Sex: All

    Nearest site: AdventHealth Neuroscience Institute (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  10. Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients

    NCT06372964

    • Phase 3
    • Ages 10 to 17 years
    • Sex: All

    Nearest site: APG Research LLC (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  11. Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

    NCT06547489

    • Phase 2
    • Ages 18 to 64 years
    • Sex: All

    Nearest site: Clinical Neuroscience Solutions, Inc. (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  12. Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

    NCT06559306

    • Phase 3
    • Ages 18 to 74 years
    • Sex: All

    Nearest site: Nova Psychiatry INC (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  13. Adapting Single Sessions Interventions for Type 1 Diabetes

    NCT06752369

    • Interventional
    • Ages 12 to 17 years
    • Sex: All

    Nearest site: Nemours Children's Hospital - FL (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  14. TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

    NCT07048574

    • Observational
    • Ages 18 months to 11 years
    • Sex: All

    Nearest site: Nemours Foundation (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  15. A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

    NCT07065240

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Seaport Investigator Site (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT07196501

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Neurocrine Clinical Site (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder

    NCT07276997

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Clinical Neuroscience Solutions - Orlando - East South Street /ID# 277558 (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

    NCT07284667

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Clinical Neuroscience Solutions, Inc. (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression

    NCT07300969

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: Draig Clinical Site (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT06966401

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Neurocrine Clinical Site (Maitland, FL); Neurocrine Clinical Site (Maitland, FL)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  21. Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT06786624

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Neurocrine Clinical Site (Maitland, FL)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

    NCT06793397

    • Phase 3
    • Ages 18 to 85 years
    • Sex: All

    Nearest site: Accel Research Sites - Maitland (Maitland, FL)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT06963021

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Neurocrine Clinical Site (Maitland, FL)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women

    NCT07413705

    • Interventional
    • Ages 40 years and older
    • Sex: Female

    Nearest site: Luxury Psychiatry Clinic (Winter Garden, FL)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Study of ALTO-300 in MDD

    NCT05922878

    • Phase 2
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: Site 159 (Clermont, FL)

    Distance to nearest recruiting site
    ~24 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

    NCT07105111

    • Phase 4
    • Ages 18 years and older
    • Sex: All

    Nearest site: Neurocrine Clinical Site (Orange City, FL)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Depression clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.