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Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics

NCT05877885

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The goal of this randomized controlled trial is to evaluate the potential of a customized digital cognitive training intervention to target aspects of brain function in apathy of late-life depression and reduce symptoms of apathy and related cognitive and behavioral deficits. The investigators hypothesize that 4 weeks of a customized digital cognitive training program will lead to changes in brain connectivity, apathy severity, and cognitive control performance.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Major Depressive Disorder
  • Apathy

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
60 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
AdventHealth
Last updated on ClinicalTrials.gov
October 22, 2025

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Florida · 1

  • AdventHealth Neuroscience Institute · Orlando, FL

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.