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Depression Clinical Trials near Dallas, TX

39 studies for Depression are recruiting at 57 sites within 50 miles of Dallas, Texas, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Depression trials in the US or all trials near Dallas.

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Depression studies enrolling near Dallas

Showing 39 studies, nearest first.
  1. A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

    NCT04777357

    • Phase 3
    • Ages 10 to 17 years
    • Sex: All

    Nearest sites: Relaro Medical Trials /ID# 227156 (Dallas, TX); Texas Research Group /ID# 270050 (Coppell, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  2. ALTO-100 in Bipolar Disorder With Depression (BD-D)

    NCT06656416

    • Phase 2
    • Ages 18 to 70 years
    • Sex: All

    Nearest sites: Site 6107 (Dallas, TX); Site 6176 (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  3. A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

    NCT07065240

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Seaport Investigator Site (Dallas, TX); Seaport Investigator Site (Irving, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  4. A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

    NCT07621237

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest sites: FutureSearch Trials of Dallas (Dallas, TX); Delricht Research - Plano (Plano, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  5. A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

    NCT03887715

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest sites: University of Texas Southwestern (Dallas, TX); Northpointe Psychiatry (Lewisville, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  6. A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

    NCT06223880

    • Phase 4
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Clinical Research Site (Dallas, TX); Clinical Research Site (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  7. Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT06966401

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Neurocrine Clinical Site (Dallas, TX); Neurocrine Clinical Site (DeSoto, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  8. Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)

    NCT03906435

    • Interventional
    • Ages Any age
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Parkland Health & Hospital System (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  9. Tractography Guided Subcallosal Cingulate Deep Brain Stimulation for Treatment Resistant Depression

    NCT03952962

    • Interventional
    • Ages 21 to 70 years
    • Sex: All

    Nearest site: UT Southwestern Medical Center (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  10. Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care

    NCT05869552

    • Interventional
    • Ages 18 to 24 years
    • Sex: All

    Nearest site: University of Texas Southwestern Medical Center (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  11. Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

    NCT06423430

    • Interventional
    • Ages 22 to 70 years
    • Sex: All

    Nearest site: University of Texas Southwestern Medical Center at Dallas (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  12. Accelerated rTMS for Substance Use Disorder and Depression

    NCT06424184

    • Interventional
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: UT Southwestern Medical Center (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  13. Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

    NCT06740383

    • Observational
    • Ages 18 to 40 years
    • Sex: All

    Nearest site: University of Texas Southwestern Medical Center (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  14. Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT06786624

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Neurocrine Clinical Site (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  15. Recovery Through Inspiration, Support, and Empowerment

    NCT07051200

    • Interventional
    • Ages 18 to 27 years
    • Sex: All

    Nearest site: The University of Texas Southwestern Medical Center (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. Teen Recovery Through Inspiration, Support, and Empowerment

    NCT07170657

    • Interventional
    • Ages 15 to 18 years
    • Sex: All

    Nearest site: The University of Texas Southwestern Medical Center (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. Parent-Adolescent Relationships, Emotional Regulation, and HRV in Adolescents With Depression

    NCT07430774

    • Observational
    • Ages 12 to 18 years
    • Sex: All

    Nearest site: Child and adolescent psychiatrist at the Children's Health Psychiatry Clinic. (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

    NCT07484217

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Clinical Research Site (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder

    NCT07573176

    • Phase 3
    • Ages 18 to 74 years
    • Sex: All

    Nearest site: Future Search Trials of Dallas (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. tDCS for Late-Life Depression

    NCT07657234

    • Phase 1/2
    • Ages 60 years and older
    • Sex: All

    Nearest site: University of Texas Southwestern Medical Center (Dallas, TX)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. ALTO-207 in Adults With Treatment-resistant Depression (TRD)

    NCT07553637

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: Site 7161 (Irving, TX)

    Distance to nearest recruiting site
    ~9 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

    NCT06830044

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Vanda Investigational Site (Richardson, TX); Vanda Investigational Site (Plano, TX)

    Distance to nearest recruiting site
    ~12 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  23. A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression

    NCT07300969

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest sites: Draig Clinical Site (Richardson, TX); Draig Clinical Site (DeSoto, TX)

    Distance to nearest recruiting site
    ~12 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  24. Brexanolone Lifting Outcomes Of Moms

    NCT07822321

    • Phase 3
    • Ages 15 to 45 years
    • Sex: Female

    Nearest sites: Lipocine Investigational Site (Richardson, TX); Lipocine Investigational Site (Plano, TX)

    Distance to nearest recruiting site
    ~12 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  25. Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

    NCT05850689

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Pillar Clinical Research, LLC (Richardson, TX)

    Distance to nearest recruiting site
    ~12 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder

    NCT07276997

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Pillar Clinical Research - Richardson /ID# 276764 (Richardson, TX)

    Distance to nearest recruiting site
    ~12 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

    NCT06524830

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: InSite Clinical Research (DeSoto, TX); Aim Trials, LLC (Plano, TX)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  28. A Study of Brenipatide in Adult Participants With Major Depressive Disorder

    NCT07412756

    • Phase 3
    • Ages 18 to 75 years
    • Sex: All

    Nearest sites: Adams Clinical Dallas (DeSoto, TX); Re:Cognition Health - Fort Worth (Fort Worth, TX)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  29. A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

    NCT07610473

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest sites: Draig Clinical Site (DeSoto, TX); Draig Clinical Site (Fort Worth, TX)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  30. Triage Survey for Psychiatry Research Eligibility

    NCT05800925

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Adams Clinical, Dallas (DeSoto, TX)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

    NCT06547489

    • Phase 2
    • Ages 18 to 64 years
    • Sex: All

    Nearest site: InSite Clinical Research, LLC (DeSoto, TX)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

    NCT06793397

    • Phase 3
    • Ages 18 to 85 years
    • Sex: All

    Nearest site: Adams Clinical Dallas (DeSoto, TX)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT06911112

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Neurocrine Clinical Site (DeSoto, TX)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder

    NCT07775300

    • Phase 3
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: Adams Clinical Dallas (DeSoto, TX)

    Distance to nearest recruiting site
    ~14 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

    NCT07048574

    • Observational
    • Ages 18 months to 11 years
    • Sex: All

    Nearest site: UT Southwestern (Plano, TX)

    Distance to nearest recruiting site
    ~18 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. Exploring Virtual Reality Adventure Training Exergaming

    NCT05563805

    • Interventional
    • Ages 18 to 45 years
    • Sex: Female
    • Accepts healthy volunteers

    Nearest site: University of Texas at Arlington (Arlington, TX)

    Distance to nearest recruiting site
    ~18 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  37. Effects of Exercise and Virtual Reality on Depression

    NCT05973461

    • Interventional
    • Ages 18 to 65 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: UTArlington (Arlington, TX)

    Distance to nearest recruiting site
    ~18 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  38. Study of ALTO-300 in MDD

    NCT05922878

    • Phase 2
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: Site 347 (Fort Worth, TX)

    Distance to nearest recruiting site
    ~30 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  39. Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

    NCT06559306

    • Phase 3
    • Ages 18 to 74 years
    • Sex: All

    Nearest site: North Texas Clinical Trials (Fort Worth, TX)

    Distance to nearest recruiting site
    ~30 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Depression clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.