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Crohn's Disease Clinical Trials near Boston, MA

30 studies for Crohn's Disease are recruiting at 41 sites within 50 miles of Boston, Massachusetts, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Crohn's Disease trials in the US or all trials near Boston.

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Recruiting now

Crohn's Disease studies enrolling near Boston

Showing 30 studies, nearest first.
  1. A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

    NCT06819878

    • Phase 3
    • Ages 16 to 80 years
    • Sex: All

    Nearest sites: Boston University (Boston, MA); Brigham and Women's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  2. An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

    NCT07184931

    • Phase 3
    • Ages 16 to 80 years
    • Sex: All

    Nearest sites: Tufts Medical Center-Site Number: 8400126 (Boston, MA); UMass Memorial Medical Center-Site Number: 8400121 (Worcester, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  3. Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

    NCT03816345

    • Phase 1
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Dana-Farber Cancer Institute (Boston, MA); Massachusetts General Hospital Cancer Center (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  4. Low Dose IL-2 for the Treatment of Crohn's Disease

    NCT04263831

    • Phase 1/2
    • Ages 12 to 80 years
    • Sex: All

    Nearest sites: Boston Children's Hospital (Boston, MA); Brigham and Women's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  5. A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

    NCT04844606

    • Phase 3
    • Ages 2 to 19 years
    • Sex: All

    Nearest sites: Boston Children's Hospital (Boston, MA); Massachusetts General Hospital (Waltham, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  6. Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

    NCT05781152

    • Phase 4
    • Ages 6 to 17 years
    • Sex: All

    Nearest sites: Boston Children's Hospital (Boston, MA); Rhode Island Hospital (Providence, RI)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  7. A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

    NCT06430801

    • Phase 3
    • Ages 16 to 80 years
    • Sex: All

    Nearest sites: Massachusetts General Hospital-Crohn's and Colitis Center ( Site 5037) (Boston, MA); University Gastroenterology - Providence - West River Street ( Site 5057) (Providence, RI)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  8. High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

    NCT04331639

    • Observational
    • Ages 5 to 25 years
    • Sex: All

    Nearest site: Boston Children's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  9. Skeletal Health and Bone Marrow Composition in Newly Diagnosed Adolescents With Crohn Disease

    NCT04508088

    • Observational
    • Ages 13 to 20 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Boston Children's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  10. Personalized Risk Estimation for Crohn's Disease (PRE-Crohn's): Implementation and Feasibility

    NCT05332639

    • Interventional
    • Ages 14 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  11. A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

    NCT05923073

    • Phase 3
    • Ages 2 to 17 years
    • Sex: All

    Nearest site: Boston Childrens Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  12. Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

    NCT06332534

    • Phase 3
    • Ages 2 to 17 years
    • Sex: All

    Nearest site: Boston Children's Hospital /ID# 262191 (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  13. Family Members at INcreased-risk for Developing Inflammatory Bowel Disease

    NCT06655415

    • Observational
    • Ages 14 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  14. A Study to Investigate Efficacy and Safety of Brivekimig in Participants With Crohn's Disease

    NCT06958536

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: Investigational Site Number: 8400022 (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  15. Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

    NCT07033208

    • Interventional
    • Ages 18 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule

    NCT07219537

    • Interventional
    • Ages 18 to 75 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Massachusetts General Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. Zymfentra (Infliximab-dyyb) REal World Cohort STudy

    NCT07237516

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: Brigham and Women's Hospital (Boston, MA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. Value of PET/MR Enterography in the Assessment of Crohn's Disease Using a Collagen-binding Radiotracer.

    NCT06252493

    • Observational
    • Ages 18 to 99 years
    • Sex: All

    Nearest site: Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School (Charlestown, MA)

    Distance to nearest recruiting site
    ~1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease

    NCT05995353

    • Phase 3
    • Ages 2 to 17 years
    • Sex: All

    Nearest site: Massachusetts General Hospital - Mass General Waltham /ID# 255767 (Waltham, MA)

    Distance to nearest recruiting site
    ~9 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting

    NCT06581328

    • Phase 4
    • Ages 18 to 80 years
    • Sex: All

    Nearest sites: Gastro Health Research - Framingham (Framingham, MA); University Gastroenterology (Providence, RI)

    Distance to nearest recruiting site
    ~19 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  21. A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

    NCT06819891

    • Phase 3
    • Ages 16 to 80 years
    • Sex: All

    Nearest sites: University of Massachusetts Memorial Medical Center (North Worcester, MA); University Gastroenterology (Providence, RI)

    Distance to nearest recruiting site
    ~39 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  22. Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

    NCT05230173

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Gastroenterology Associates (Providence, RI)

    Distance to nearest recruiting site
    ~41 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  23. A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

    NCT06045754

    • Phase 4
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: University Gastroenterology (Providence, RI)

    Distance to nearest recruiting site
    ~41 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  24. A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

    NCT06233461

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: University Gastroenterology Providence (Providence, RI)

    Distance to nearest recruiting site
    ~41 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

    NCT06937099

    • Phase 3
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: University Gastroenterology (Providence, RI)

    Distance to nearest recruiting site
    ~41 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

    NCT07113522

    • Phase 2
    • Ages 18 to 80 years
    • Sex: All

    Nearest site: Mirador Therapeutics Selected Site (Providence, RI)

    Distance to nearest recruiting site
    ~41 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

    NCT07184944

    • Phase 3
    • Ages 16 to 80 years
    • Sex: All

    Nearest site: University Gastroenterology - GI Alliance-Site Number: 8400103 (Providence, RI)

    Distance to nearest recruiting site
    ~41 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

    NCT07196722

    • Phase 2/3
    • Ages 18 years and older
    • Sex: All

    Nearest site: University Gastroenterology (Providence, RI)

    Distance to nearest recruiting site
    ~41 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. NOV-ERA - A Clinical Trial to Assess the Efficacy and Safety of Ontunisertib Compared to Placebo in Patients With Fibrostenosing Crohn's Disease

    NCT07683325

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: University Gastroenterology (Providence, RI)

    Distance to nearest recruiting site
    ~41 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

    NCT07697456

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: University Gastroenterology - Providence - Staniford Street /ID# 280919 (Providence, RI)

    Distance to nearest recruiting site
    ~41 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Crohn's Disease clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.