A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
NCT06430801
This study is recruiting at 71 US sites in 30 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Crohn's Disease
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 16 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Merck Sharp & Dohme LLC
- Last updated on ClinicalTrials.gov
- October 13, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 2
- GI Alliance - Sun City ( Site 5118) · Sun City, AZ
- University of Arizona Clinical and Translational Sciences Research Center ( Site 5111) · Tucson, AZ
Arkansas · 1
- University of Arkansas for Medical Sciences ( Site 5147) · Little Rock, AR
California · 8
- Clinnova Research ( Site 5110) · Anaheim, CA
- Southern California Research Center ( Site 5044) · Coronado, CA
- Om Research LLC ( Site 5038) · Lancaster, CA
- Cedars Sinai Medical Center ( Site 5080) · Los Angeles, CA
- UCLA Clinical & Translational Research Center (CTRC) ( Site 5116) · Los Angeles, CA
- University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 5128) · Orange, CA
- Om Research LLC ( Site 5045) · Oxnard, CA
- Clinical Applications Laboratories ( Site 5123) · San Diego, CA
Colorado · 4
- University of Colorado Anschutz Medical Campus-Division of Gastroenterology and Hepatology ( Site 5026) · Aurora, CO
- Peak Gastroenterology Associates ( Site 5023) · Colorado Springs, CO
- South Denver Gastroenterology, PC ( Site 5132) · Englewood, CO
- Rocky Mountain Gastroenterology ( Site 5082) · Lakewood, CO
Connecticut · 1
- Yale University School of Medicine-Digestive Disease ( Site 5019) · New Haven, CT
District of Columbia · 1
- Emerson Clinical Research Institute ( Site 5051) · Washington D.C., DC
Florida · 7
- Covenant Metabolic Specialists, LLC ( Site 5150) · Fort Myers, FL
- Nature Coast Clinical Research - Inverness ( Site 5042) · Inverness, FL
- Sanchez Clinical Research ( Site 5144) · Miami, FL
- AdventHealth Orlando ( Site 5131) · Orlando, FL
- Endoscopic Research Inc ( Site 5061) · Orlando, FL
- USF Health Carol and Frank Morsani Center for Advanced Healthcare ( Site 5039) · Tampa, FL
- Covenant Metabolic Specialists, LLC ( Site 5143) · University Park, FL
Georgia · 2
- Morehouse School Of Medicine ( Site 5071) · Atlanta, GA
- Gastroenterology Associates of Central Georgia ( Site 5048) · Macon, GA
Illinois · 3
- University of Chicago Medical Center ( Site 5066) · Chicago, IL
- Endeavor Health ( Site 5018) · Evanston, IL
- GI ALLIANCE - GURNEE ( Site 5003) · Gurnee, IL
Indiana · 1
- Indiana University Health University Hospital ( Site 5022) · Indianapolis, IN
Iowa · 1
- Iowa Digestive Disease Center ( Site 5007) · Clive, IA
Kansas · 2
- University of Kansas Medical Center ( Site 5091) · Kansas City, KS
- Cotton O'Neil Digestive Health Center ( Site 5033) · Topeka, KS
Kentucky · 1
- University of Louisville Hospital ( Site 5120) · Louisville, KY
Maryland · 1
- Walter Reed National Military Medical Center ( Site 5006) · Bethesda, MD
Massachusetts · 1
- Massachusetts General Hospital-Crohn's and Colitis Center ( Site 5037) · Boston, MA
Michigan · 2
- University of Michigan ( Site 5060) · Ann Arbor, MI
- Clinical Research Institute of Michigan, LLC ( Site 5002) · Clinton Township, MI
Minnesota · 1
- Mayo Clinic in Rochester, Minnesota ( Site 5024) · Rochester, MN
Missouri · 3
- Mid-America GI Clinical Research ( Site 5130) · Kansas City, MO
- BVL Research - Kansas ( Site 5099) · Liberty, MO
- Washington University School of Medicine ( Site 5058) · St Louis, MO
New Jersey · 1
- HMH Justice Marie Garibaldi Medical Plaza ( Site 5072) · Hackensack, NJ
New York · 5
- Northwell Health Physician Partners Center for Advanced IBD Care ( Site 5017) · Great Neck, NY
- New York Gastroenterology Associates ( Site 5013) · New York, NY
- NYU Langone Health - Inflammatory Bowel Disease Center (IBD) ( Site 5078) · New York, NY
- Weill Cornell Medical College, New-York Presbyterian Hospital ( Site 5079) · New York, NY
- Northwell Mather Hospital ( Site 5138) · Port Jefferson, NY
North Carolina · 2
- University of North Carolina Medical Center ( Site 5034) · Chapel Hill, NC
- Atrium Health Gastroenterology MMP ( Site 5105) · Charlotte, NC
Ohio · 1
- Great Lakes Gastroenterology Research, LLC ( Site 5016) · Mentor, OH
Oklahoma · 1
- Digestive Disease Specialists Inc. ( Site 5117) · Oklahoma City, OK
Pennsylvania · 3
- Penn State University Milton S. Hershey Medical Center ( Site 5102) · Hershey, PA
- Thomas Jefferson University Hospital ( Site 5133) · Philadelphia, PA
- Frontier Clinical Research, LLC ( Site 5098) · Uniontown, PA
Rhode Island · 1
- University Gastroenterology - Providence - West River Street ( Site 5057) · Providence, RI
South Dakota · 1
- Sanford USD Medical Center ( Site 5129) · Sioux Falls, SD
Tennessee · 2
- Quality Medical Research ( Site 5114) · Nashville, TN
- Vanderbilt Inflammatory Bowel Disease Clinic ( Site 5049) · Nashville, TN
Texas · 9
- Baylor University Medical Center ( Site 5031) · Dallas, TX
- Epic Medical Research - Mesquite ( Site 5153) · Denton, TX
- Baylor College of Medicine Medical Center ( Site 5020) · Houston, TX
- Michael E. DeBakey VA Medical Center ( Site 5086) · Houston, TX
- Caprock Gastro Research ( Site 5077) · Lubbock, TX
- GI Alliance: Mansfield ( Site 5015) · Mansfield, TX
- Southern Star Research Institute ( Site 5000) · San Antonio, TX
- GI Alliance - Southlake ( Site 5109) · Southlake, TX
- Tyler Research Institute ( Site 5001) · Tyler, TX
Virginia · 1
- Richmond VA Medical Center ( Site 5021) · Richmond, VA
Washington · 2
- University of Washington ( Site 5115) · Seattle, WA
- Washington Gastroenterology - Tacoma ( Site 5004) · Tacoma, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.