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Alzheimer's Disease Clinical Trials near Orlando, FL

35 studies for Alzheimer's Disease are recruiting at 88 sites within 50 miles of Orlando, Florida, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Alzheimer's Disease trials in the US or all trials near Orlando.

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Recruiting now

Alzheimer's Disease studies enrolling near Orlando

Showing 35 studies, nearest first.
  1. A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

    NCT07602582

    • Phase 3
    • Ages 55 years and older
    • Sex: All

    Nearest sites: Charter Research - Orlando (Orlando, FL); Headlands Research Orlando (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    8 sites within 50 mi
  2. Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

    NCT07177352

    • Phase 3
    • Ages 50 to 90 years
    • Sex: All

    Nearest sites: Charter Research - Winter Park/Orlando (Orlando, FL); Conquest Research - Lake Nona (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    7 sites within 50 mi
  3. Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

    NCT06584357

    • Observational
    • Ages 60 to 90 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Charter Research (Orlando, FL); Conquest Research (Winter Park, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  4. A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

    NCT06585787

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest sites: Charter Research Orlando (Orlando, FL); Combined Research Orlando Phase I-IV LLC (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  5. A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease

    NCT07717411

    • Phase 3
    • Ages 55 to 80 years
    • Sex: All

    Nearest sites: Charter Research - Winter Park/Orlando (Orlando, FL); Conquest Research - Lake Nona (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  6. Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

    NCT05980949

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest sites: Combined Research Orlando Phase I-IV LLC (Orlando, FL); Nova Psychiatry (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  7. A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

    NCT07033494

    • Phase 2
    • Ages 50 to 85 years
    • Sex: All

    Nearest sites: Charter Research - Orlando ( Site 1051) (Orlando, FL); Conquest Research LLC ( Site 1053) (Winter Park, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  8. A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

    NCT05462106

    • Phase 1/2
    • Ages 35 to 85 years
    • Sex: All

    Nearest sites: Charter Research, LLC (Orlando, FL); K2 Medical Research The Villages LLC (Lady Lake, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  9. A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia

    NCT06651567

    • Phase 2
    • Ages 55 years and older
    • Sex: All

    Nearest sites: Charter Research (Orlando, FL); K2 Medical Research (Maitland, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  10. A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

    NCT07011732

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest sites: Combined Research Orlando (CRO) (Orlando, FL); Flourish Research (Merritt Island, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  11. A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

    NCT07589595

    • Phase 2
    • Ages 55 to 85 years
    • Sex: All

    Nearest sites: Charter Research - Orlando (Orlando, FL); Conquest Research (Winter Park, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  12. Clinical Study of SNK01 in Participants With Moderate Alzheimer's Disease

    NCT06189963

    • Phase 1/2
    • Ages 40 to 85 years
    • Sex: All

    Nearest sites: AdventHealth Research Institute (Orlando, FL); K2 Medical Research (Maitland, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  13. Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease

    NCT06847321

    • Phase 2
    • Ages 55 to 80 years
    • Sex: All

    Nearest sites: Conquest Research - Lake Nona (Orlando, FL); Progressive Medical Research (Port Orange, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  14. ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease

    NCT03671889

    • Interventional
    • Ages 50 to 85 years
    • Sex: All

    Nearest site: Advent Health (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  15. ACP-204 in Adults With Alzheimer's Disease Psychosis

    NCT06159673

    • Phase 2/3
    • Ages 55 to 95 years
    • Sex: All

    Nearest site: Combined Research Orlando Phase I IV (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. University of Central Florida CereBank

    NCT06876857

    • Observational
    • Ages 18 years and older
    • Sex: Female
    • Accepts healthy volunteers

    Nearest site: University of Central Florida (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

    NCT06887192

    • Phase 2
    • Ages 55 to 90 years
    • Sex: All

    Nearest site: Clinical Site (Orlando, FL)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

    NCT07094516

    • Phase 2
    • Ages 50 to 85 years
    • Sex: All

    Nearest sites: Conquest Research (Winter Park, FL); K2 Medical Research LLC (Maitland, FL)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  19. [18F]PI-2620 Phase 3 Histopathological Study

    NCT05641688

    • Phase 3
    • Ages 50 years and older
    • Sex: All

    Nearest sites: Charter Research (Winter Park, FL); K2 Medical Research (Maitland, FL)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  20. A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease

    NCT07599670

    • Phase 1/2
    • Ages 50 to 90 years
    • Sex: All

    Nearest sites: Conquest Research - Winter Park /ID# 277760 (Winter Park, FL); K2 Medical Research - Clermont /ID# 277859 (Clermont, FL)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  21. Low-Dose Radiotherapy for Alzheimer's Disease

    NCT07693140

    • Phase 1/2
    • Ages 50 years and older
    • Sex: All

    Nearest site: Renaissance Institute of Precision Oncology & Radiosurgery (Winter Park, FL)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

    NCT05511363

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest sites: K2 Medical Research - Maitland (Maitland, FL); K2 Medical Research - Winter Garden (Clermont, FL)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  23. A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

    NCT06297590

    • Phase 1
    • Ages 50 to 85 years
    • Sex: All

    Nearest sites: K2 Medical Research, LLC (Maitland, FL); Charter Research, LLC (The Villages, FL)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  24. A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)

    NCT06657768

    • Phase 1
    • Ages 45 to 85 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: K2 Medical Research (Maitland, FL); K2 Medical Research - The Villages (Lady Lake, FL)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  25. Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

    NCT06808984

    • Phase 2
    • Ages 55 to 90 years
    • Sex: All

    Nearest sites: ClinCloud (Maitland, FL); Charter Research - Lady Lake (The Villages, FL)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  26. A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease

    NCT06540833

    • Phase 2
    • Ages 55 years and older
    • Sex: All

    Nearest site: K2 Medical Research (Maitland, FL)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. Open-label Extension Study in Participants With Early Alzheimer's Disease

    NCT07105709

    • Phase 2
    • Ages 50 to 85 years
    • Sex: All

    Nearest site: GSK Investigational Site (Maitland, FL)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)

    NCT07636811

    • Phase 2
    • Ages 40 to 55 years
    • Sex: All

    Nearest site: Clinical Trial Site (Maitland, FL)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. An Open Label Dose Escalation Study of VY1706 in Participants With Early Alzheimer's Disease

    NCT07764146

    • Phase 1
    • Ages 30 to 80 years
    • Sex: All

    Nearest site: K2 Medical Research, LLC (Maitland, FL)

    Distance to nearest recruiting site
    ~6 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

    NCT06976203

    • Phase 3
    • Ages 60 to 85 years
    • Sex: All

    Nearest site: K2 MEDICAL Research THE VILLAGES (Lady Lake, FL)

    Distance to nearest recruiting site
    ~42 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

    NCT06976216

    • Phase 3
    • Ages 60 to 85 years
    • Sex: All

    Nearest sites: Merritt Island Medical Research, LLC (Merritt Island, FL); Charter Research - Lady Lake (The Villages, FL)

    Distance to nearest recruiting site
    ~44 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  32. A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)

    NCT06126224

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest site: Local Institution - 1131 (Viera, FL)

    Distance to nearest recruiting site
    ~44 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease

    NCT07688213

    • Phase 2
    • Ages 55 to 85 years
    • Sex: All

    Nearest site: Charter Research - Lady Lake- Site Number : 8400004 (The Villages, FL)

    Distance to nearest recruiting site
    ~45 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

    NCT06937229

    • Phase 3
    • Ages 55 to 90 years
    • Sex: All

    Nearest site: Progressive Medical Research (Port Orange, FL)

    Distance to nearest recruiting site
    ~48 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

    NCT07633470

    • Phase 4
    • Ages 50 years and older
    • Sex: All

    Nearest site: Progressive Medical Research (Port Orange, FL)

    Distance to nearest recruiting site
    ~48 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining an Alzheimer's Disease clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.