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Depression Clinical Trials near Bethesda, MD

46 studies for Depression are recruiting at 76 sites within 50 miles of Bethesda, Maryland, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Depression trials in the US or all trials near Bethesda.

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Depression studies enrolling near Bethesda

Showing 46 studies, nearest first.
  1. Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders

    NCT00018057

    • Phase 2
    • Ages 8 to 65 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: National Institutes of Health Clinical Center (Bethesda, MD); University of Maryland, College Park (College Park, MD)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  2. Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

    NCT00024635

    • Observational
    • Ages 3 to 99 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: National Institutes of Health Clinical Center (Bethesda, MD)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  3. Neurobiology of Suicide

    NCT02543983

    • Phase 2
    • Ages 18 to 70 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: National Institutes of Health Clinical Center (Bethesda, MD)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  4. Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

    NCT03065335

    • Phase 1
    • Ages 18 to 65 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: National Institutes of Health Clinical Center (Bethesda, MD)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  5. Characterization and Treatment of Adolescent Depression

    NCT03388606

    • Observational
    • Ages 11 to 25 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: National Institutes of Health Clinical Center (Bethesda, MD)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  6. Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression

    NCT03973268

    • Phase 1
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: National Institutes of Health Clinical Center (Bethesda, MD)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  7. PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)

    NCT04582916

    • Phase 1
    • Ages 18 to 70 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: National Institutes of Health Clinical Center (Bethesda, MD)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  8. Long-term Observation of Participants With Mood Disorders

    NCT04877977

    • Observational
    • Ages 18 to 99 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: National Institutes of Health Clinical Center (Bethesda, MD)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  9. CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

    NCT05663034

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Walter Reed National Medical Military Center (Bethesda, MD)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  10. NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar Disorder

    NCT05669703

    • Observational
    • Ages 8 to 70 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: National Institutes of Health Clinical Center (Bethesda, MD)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  11. [18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET

    NCT05703685

    • Phase 1
    • Ages 18 to 70 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: National Institutes of Health Clinical Center (Bethesda, MD)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  12. Natural History of Depression, Bipolar Disorder and Suicide Risk

    NCT06462196

    • Observational
    • Ages 18 to 120 years
    • Sex: All

    Nearest site: National Institutes of Health Clinical Center (Bethesda, MD)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  13. Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

    NCT06511908

    • Phase 2
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: National Institutes of Health Clinical Center (Bethesda, MD)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  14. Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)

    NCT07149428

    • Observational
    • Ages 18 to 99 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: National Institutes of Health Clinical Center (Bethesda, MD)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  15. E-Mindfulness Approaches for Living After Breast Cancer

    NCT06748222

    • Phase 3
    • Ages 18 to 50 years
    • Sex: All

    Nearest sites: Kaiser Permanente Tysons Corner Medical Center (McLean, VA); Kaiser Permanente-Capitol Hill Medical Center (Washington D.C., DC)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    24 sites within 50 mi
  16. A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder

    NCT07227454

    • Phase 3
    • Ages 12 to 17 years
    • Sex: All

    Nearest sites: Children's National Medical Center (Washington D.C., DC); Johns Hopkins University (Baltimore, MD)

    Distance to nearest recruiting site
    ~7 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  17. Mindful Self-Compassion for Anxiety Disorders and Depression

    NCT05671419

    • Interventional
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: Georgetown University Medical Center (Washington D.C., DC)

    Distance to nearest recruiting site
    ~7 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. Does Social Media Impact Adolescent Mental Health?

    NCT06049888

    • Interventional
    • Ages 10 to 14 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Georgetown University (Washington D.C., DC)

    Distance to nearest recruiting site
    ~7 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. Pragmatic Clinic-Based Trial of a Mindfulness Based Intervention for Mood Concerns in Youth With Type 1 Diabetes

    NCT06618027

    • Interventional
    • Ages 13 to 17 years
    • Sex: All

    Nearest site: Children&#39;s National Hospital (Washington D.C., DC)

    Distance to nearest recruiting site
    ~7 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. The Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic

    NCT06623981

    • Interventional
    • Ages Any age
    • Sex: All

    Nearest site: Children's National Hospital (Washington D.C., DC)

    Distance to nearest recruiting site
    ~7 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method

    NCT07028216

    • Interventional
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Georgetown University Medical Center (Washington D.C., DC)

    Distance to nearest recruiting site
    ~7 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

    NCT06524830

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Sunstone Medical, PC (Rockville, MD); Sheppard Pratt (Baltimore, MD)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  23. RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

    NCT07002034

    • Phase 2
    • Ages 18 to 80 years
    • Sex: All

    Nearest sites: Sunstone Therapies, PC (Rockville, MD); Sheppard Pratt (Towson, MD)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  24. A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

    NCT07621237

    • Phase 2
    • Ages 18 years and older
    • Sex: All

    Nearest site: Delricht Research - Rockville (Rockville, MD)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  25. Clinical Validation of a Predictive Test for Postpartum Depression

    NCT06831968

    • Observational
    • Ages 18 years and older
    • Sex: Female
    • Accepts healthy volunteers

    Nearest site: Inova Health System (Falls Church, VA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. ALTO-100 in Bipolar Disorder With Depression (BD-D)

    NCT06656416

    • Phase 2
    • Ages 18 to 70 years
    • Sex: All

    Nearest sites: Site 6062 (Gaithersburg, MD); Site 6177 (Fairfax, VA)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  27. Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

    NCT06966401

    • Phase 3
    • Ages 18 years and older
    • Sex: All

    Nearest site: Neurocrine Clinical Site (Gaithersburg, MD)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression

    NCT07300969

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: Draig Clinical Site (Gaithersburg, MD)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. A Study of Brenipatide in Adult Participants With Major Depressive Disorder

    NCT07412756

    • Phase 3
    • Ages 18 to 75 years
    • Sex: All

    Nearest sites: Re:Cognition Health (Fairfax, VA); Pharmasite Research, Inc. (Baltimore, MD)

    Distance to nearest recruiting site
    ~15 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  30. Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)

    NCT06633016

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Autobahn Site #145 (Fairfax, VA)

    Distance to nearest recruiting site
    ~15 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. Evaluating Conversational Artificial Intelligence for Depression Management

    NCT07105397

    • Interventional
    • Ages 18 to 85 years
    • Sex: All

    Nearest site: George Mason University (Fairfax, VA)

    Distance to nearest recruiting site
    ~15 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. rTMS for Military TBI-related Depression

    NCT05426967

    • Interventional
    • Ages 18 to 55 years
    • Sex: All

    Nearest site: Alexander T. Augusta Military Medical Center (Fort Belvoir, VA)

    Distance to nearest recruiting site
    ~19 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. ALTO-207 in Adults With Treatment-resistant Depression (TRD)

    NCT07553637

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: Site 7151 (Annapolis, MD)

    Distance to nearest recruiting site
    ~33 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

    NCT03887715

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Sheppard Pratt Health System, Inc. (Baltimore, MD)

    Distance to nearest recruiting site
    ~34 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

    NCT04123314

    • Early Phase 1
    • Ages 18 to 85 years
    • Sex: All

    Nearest site: Johns Hopkins Center for Psychedelic and Consciousness Research (Baltimore, MD)

    Distance to nearest recruiting site
    ~34 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  36. Defining Neurobiological Links Between Substance Use and Mental Illness

    NCT05538910

    • Interventional
    • Ages 18 to 60 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: National Institute on Drug Abuse (Baltimore, MD)

    Distance to nearest recruiting site
    ~34 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  37. CAPABLE Transplant

    NCT06326905

    • Interventional
    • Ages 18 to 99 years
    • Sex: All

    Nearest site: Johns Hopkins School of Nursing (Baltimore, MD)

    Distance to nearest recruiting site
    ~34 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  38. Psilocybin in Chronic Low Back Pain and Depression

    NCT06355414

    • Phase 1
    • Ages 21 to 80 years
    • Sex: All

    Nearest site: Johns Hopkins University School of Medicine (Baltimore, MD)

    Distance to nearest recruiting site
    ~34 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  39. Change in Social Media Use and Well-being Among College Students Receiving a Two-week Exercise or Mindfulness Intervention

    NCT07097545

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Johns Hopkins University (Baltimore, MD)

    Distance to nearest recruiting site
    ~34 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  40. Being Safe, Healthy, And Positively Empowered (BSHAPE) Intervention Study

    NCT07227337

    • Interventional
    • Ages 18 years and older
    • Sex: Female

    Nearest site: Johns Hopkins University (Baltimore, MD)

    Distance to nearest recruiting site
    ~34 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  41. Strength and Pain-Coping Through Resilience and Knowledge

    NCT07228520

    • Interventional
    • Ages 50 years and older
    • Sex: All

    Nearest site: Johns Hopkins School of Nursing (Baltimore, MD)

    Distance to nearest recruiting site
    ~34 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  42. VR-PMR for Post-Burn Symptoms

    NCT07317271

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Johns Hopkins Bayview Medical Center (Baltimore, MD)

    Distance to nearest recruiting site
    ~34 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  43. A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder

    NCT07573176

    • Phase 3
    • Ages 18 to 74 years
    • Sex: All

    Nearest site: Pharmasite Research, Inc. (Baltimore, MD)

    Distance to nearest recruiting site
    ~34 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  44. A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder

    NCT07775300

    • Phase 3
    • Ages 18 to 75 years
    • Sex: All

    Nearest site: Pharmasite Research, Inc. (Baltimore, MD)

    Distance to nearest recruiting site
    ~34 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  45. Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

    NCT07484217

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Clinical Research Site (Pikesville, MD)

    Distance to nearest recruiting site
    ~34 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  46. A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

    NCT07115329

    • Phase 2
    • Ages 18 to 64 years
    • Sex: All

    Nearest site: Continental Clinical Solutions (Towson, MD)

    Distance to nearest recruiting site
    ~40 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Depression clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.