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Schizophrenia Clinical Trials near Orange, CA

35 studies for Schizophrenia are recruiting at 95 sites within 50 miles of Orange, California, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Schizophrenia trials in the US or all trials near Orange.

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Recruiting now

Schizophrenia studies enrolling near Orange

Showing 35 studies, nearest first.
  1. A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia

    NCT07459647

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Clinical Site (Orange, CA); Clinical Site (Garden Grove, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    13 sites within 50 mi
  2. A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

    NCT07105111

    • Phase 4
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Neurocrine Clinical Site (Orange, CA); Neurocrine Clinical Site (Chino, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  3. Study of ALTO-101 in Patients With Schizophrenia

    NCT06502964

    • Phase 2
    • Ages 21 to 55 years
    • Sex: All

    Nearest sites: Site 5106 (Orange, CA); Site 5038 (Garden Grove, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  4. A Study to Evaluate the Effect of KarXT on Urological Safety

    NCT07221877

    • Phase 4
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: ATP Clinical Research (Orange, CA); CenExel CNS - Garden Grove (Garden Grove, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  5. Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)

    NCT07101094

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest site: ATP Clinical Research - Costa Mesa (Orange, CA)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  6. Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder

    NCT06229210

    • Phase 3
    • Ages 5 to 17 years
    • Sex: All

    Nearest sites: Advanced Research Center, Inc (Anaheim, CA); National Institute Of Clinical Research (Garden Grove, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    5 sites within 50 mi
  7. NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia

    NCT06963034

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Neurocrine Clinical Site (Anaheim, CA); Neurocrine Clinical Site (Pico Rivera, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  8. 52-week Open Label Safety-Tolerability Study

    NCT07369154

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Advanced Research Center (Anaheim, CA); Synapse Clinical Trials (Cerritos, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  9. A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)

    NCT07288567

    • Phase 3
    • Ages 13 to 17 years
    • Sex: All

    Nearest sites: Advanced Research Center Inc. (Anaheim, CA); Inland Psychiatric Medical Group. (Chino, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  10. A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents

    NCT07424404

    • Phase 3
    • Ages 5 to 17 years
    • Sex: All

    Nearest sites: Advanced Research Center Inc. (Anaheim, CA); Inland Psychiatric Medical Group. (Chino, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  11. Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)

    NCT07379827

    • Observational
    • Ages 18 years and older
    • Sex: All

    Nearest sites: Pamoja Advanced Nursing Practice (Anaheim, CA); Inland Psychiatric Medical Group (IPMG)-Chino (Chino, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  12. Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder

    NCT05025605

    • Phase 1
    • Ages 10 to 17 years
    • Sex: All

    Nearest site: BioXcel Clinical Research Site (Anaheim, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  13. NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia

    NCT07114874

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Neurocrine Clinical Site (Garden Grove, CA); Neurocrine Clinical Site (La Habra, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    9 sites within 50 mi
  14. Efficacy of NBI-1117568 in Preventing Relapse in Adults With Schizophrenia

    NCT07227818

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Neurocrine Clinical Site (Garden Grove, CA); Neurocrine Clinical Site (La Habra, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  15. A Study of Brenipatide in Adult Participants With Schizophrenia

    NCT07410507

    • Phase 2
    • Ages 18 to 55 years
    • Sex: All

    Nearest sites: Collaborative Neuroscience Research, LLC (Garden Grove, CA); Clinical Innovations, Inc. dba CITrials (Bellflower, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  16. Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic Medications

    NCT07565428

    • Phase 3
    • Ages 18 to 55 years
    • Sex: All

    Nearest sites: Collaborative Neuroscience Research, LLC (Garden Grove, CA); Clinical Innovations, Inc. dba CITrials (Bellflower, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    4 sites within 50 mi
  17. NBI-1117568-SCZ3030: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia

    NCT07105098

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Neurocrine Clinical Site (Garden Grove, CA); Neurocrine Clinical Site (Riverside, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  18. Study to Evaluate LB-102 for the Treatment of Adult Patients With Acute Schizophrenia

    NCT07363577

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: CenExel (Garden Grove, CA); Clinical Innovations, Inc. (Riverside, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  19. Safety and Efficacy of Brilaroxazine (RP5063) in Schizophrenia

    NCT05184335

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest sites: Reviva site (Garden Grove, CA); Reviva site (Riverside, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  20. A Study of the Feasibility, Safety and Tolerability of Aticaprant as Adjunctive Treatment in Participants With Schizophrenia

    NCT07615426

    • Phase 1
    • Ages 18 to 55 years
    • Sex: All

    Nearest site: CNS Network (Garden Grove, CA)

    Distance to nearest recruiting site
    ~5 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. Cognitive Neurocomputational Task Reliability & Clinical Applications Consortium (CNTRACS): Study 1

    NCT07853807

    • Interventional
    • Ages 18 to 59 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: University of California, Irvine (Irvine, CA)

    Distance to nearest recruiting site
    ~8 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  22. Randomized Withdrawal Study in Patients With Schizophrenia

    NCT06961968

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: Vanda Investigational Site (Costa Mesa, CA); Vanda Investigational Site (Pico Rivera, CA)

    Distance to nearest recruiting site
    ~11 mi (city-level)
    Recruiting sites
    3 sites within 50 mi
  23. A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia

    NCT07145918

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest sites: CenExel Collaborative Neuroscience Research /ID# 273005 (Los Alamitos, CA); California Clinical Trials Medical Group - Parexel /ID# 275751 (Glendale, CA)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  24. A Study to Evaluate KYN-5356 in Adults With Cognitive Impairment Associated With Schizophrenia

    NCT07191483

    • Phase 2
    • Ages 18 to 55 years
    • Sex: All

    Nearest sites: Cenexel CNS (Los Alamitos, CA); Synapse Clinical Trials (Cerritos, CA)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    2 sites within 50 mi
  25. A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXT

    NCT07061288

    • Phase 1
    • Ages 18 to 55 years
    • Sex: All

    Nearest site: Collaborative Neuroscience Research, LLC (Los Alamitos, CA)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  26. Single and Multiple Ascending Doses of NTX-253 in Healthy Participants and Participants With Stable Schizophrenia

    NCT07344948

    • Early Phase 1
    • Ages 18 to 55 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Collaborative Neuroscience Research, LLC - CenExel (Los Alamitos, CA)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  27. A Study of LTX-001 In Adult Participants With Acute Exacerbation of Schizophrenia

    NCT07734493

    • Phase 1
    • Ages 18 to 55 years
    • Sex: All

    Nearest site: Collaborative Neuroscience Research, LLC (Los Alamitos, CA)

    Distance to nearest recruiting site
    ~13 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  28. Study to Assess the Safety, Tolerability, and Treatment Response of GXV813 in Hospitalized Adults With Schizophrenia

    NCT07467993

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: CNRI Los Angeles LLC (Pico Rivera, CA)

    Distance to nearest recruiting site
    ~19 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  29. Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial

    NCT05208190

    • Phase 4
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: University of California, Los Angeles (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  30. Tolerability of MDMA in Schizophrenia

    NCT05770375

    • Phase 1/2
    • Ages 18 to 60 years
    • Sex: All

    Nearest site: UCLA (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  31. Low-dose Buprenorphine as a Modulator of Social Motivation in Schizophrenia

    NCT05778591

    • Phase 2
    • Ages 18 to 60 years
    • Sex: All

    Nearest site: UCLA Semel Institute (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  32. Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode

    NCT05890183

    • Interventional
    • Ages 18 to 45 years
    • Sex: All

    Nearest site: UCLA Aftercare Research Program (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  33. Inter-Brain Synchrony in Schizophrenia

    NCT07177261

    • Interventional
    • Ages 18 to 65 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: University of California, Los Angeles (Los Angeles, CA)

    Distance to nearest recruiting site
    ~29 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  34. An Adaptive Phase II/III, Two-Part, Double-Blind, Randomized, Placebo-controlled, Dose-Finding, Multi-center Study of the Safety and Efficacy of NaBen®, as an Add-on Therapy With Clozapine, for Residual Symptoms of Refractory Schizophrenia in Adults

    NCT03094429

    • Phase 2/3
    • Ages 18 to 55 years
    • Sex: All

    Nearest site: For additional information regarding investigative sites for this trial, contact SyneuRx International Corp. (Pasadena, CA)

    Distance to nearest recruiting site
    ~30 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  35. MI-CBTech: A Mobile Intervention for Community Integration in Homeless-Experienced Veterans With SMI

    NCT06138054

    • Interventional
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: VA Greater Los Angeles Healthcare System, West Los Angeles, CA (West Los Angeles, CA)

    Distance to nearest recruiting site
    ~38 mi (city-level)
    Recruiting sites
    1 site within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Schizophrenia clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.