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Low-dose Buprenorphine as a Modulator of Social Motivation in Schizophrenia

NCT05778591

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Low social motivation is a significant symptom of schizophrenia and is a major cause of disability and suffering for many patients struggling with the illness. Social motivation refers to the drive to participate in or abstain from social activities. Many patients with schizophrenia evidence both decreased drive to seek positive social input (approach motivation) and heightened drive to avoid negative social input (avoidance motivation) compared to individuals without the illness.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Schizophrenia

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 to 60 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
University of California, Los Angeles
Last updated on ClinicalTrials.gov
April 28, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 1

  • UCLA Semel Institute · Los Angeles, CA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.