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Insomnia Clinical Trials Recruiting in the US

106 studies for Insomnia are recruiting at 200 US sites, according to ClinicalTrials.gov data processed .

Insomnia is a common sleep condition that makes it hard to fall asleep, stay asleep or both.

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Recruiting now

Top Insomnia studies by number of US sites

Showing 30 studies, most US recruiting sites first.
  1. Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)

    NCT06568367

    • Phase 3
    • Ages 18 to 65 years
    • Sex: All
    Recruiting sites
    41 US recruiting sites
  2. Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia

    NCT06953869

    • Phase 3
    • Ages 2 to 17 years
    • Sex: All
    Recruiting sites
    20 US recruiting sites
  3. A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)

    NCT06655883

    • Phase 3
    • Ages 18 to 70 years
    • Sex: All
    Recruiting sites
    13 US recruiting sites
  4. CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

    NCT05663034

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    5 US recruiting sites
  5. Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress

    NCT03642028

    • Phase 4
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    4 US recruiting sites
  6. Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

    NCT04278404

    • Observational
    • Ages 0 to 20 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    4 US recruiting sites
  7. The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer

    NCT05780814

    • Interventional
    • Ages 18 years and older
    • Sex: Female
    Recruiting sites
    4 US recruiting sites
  8. Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms

    NCT07136415

    • Phase 4
    • Ages 40 to 62 years
    • Sex: Female
    Recruiting sites
    4 US recruiting sites
  9. Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia

    NCT06281756

    • Early Phase 1
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    3 US recruiting sites
  10. Parent-Mediated Telehealth Intervention for Insomnia in Young Autistic Children

    NCT07435740

    • Interventional
    • Ages 3 to 7 years
    • Sex: All
    Recruiting sites
    3 US recruiting sites
  11. Multi-center Trial to Improve Nocturia and Sleep in Older Adults

    NCT06110091

    • Interventional
    • Ages 60 years and older
    • Sex: All
    Recruiting sites
    2 US recruiting sites
  12. Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

    NCT06609369

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All
    Recruiting sites
    2 US recruiting sites
  13. Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study

    NCT07196436

    • Interventional
    • Ages 5 years and older
    • Sex: All
    Recruiting sites
    2 US recruiting sites
  14. Cereset Research Exploratory Study

    NCT03777267

    • Interventional
    • Ages 11 years and older
    • Sex: All
    Recruiting sites
    1 US recruiting site
  15. Effects of THC-Free CBD Oil on Agitation in Patients With Alzheimer's Disease

    NCT04436081

    • Phase 2
    • Ages 50 to 90 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  16. Targeting Insomnia in School Aged Children With Autism Spectrum Disorder

    NCT04545606

    • Interventional
    • Ages 6 to 12 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  17. Sleep Trial to Prevent Alzheimer's Disease

    NCT04629547

    • Phase 2
    • Ages 65 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  18. Web-based Cognitive Behavioral Treatment for Insomnia in Dementia Caregivers

    NCT04632628

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  19. NiteCAPP: Web-based Interventions for Insomnia in Rural Dementia Caregivers

    NCT04896775

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    1 US recruiting site
  20. Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep

    NCT04953559

    • Interventional
    • Ages 18 to 50 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  21. OBSERVE: Biomarkers in Individuals at Risk for Prion Disease

    NCT05124392

    • Observational
    • Ages 18 to 85 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  22. Treatments for Insomnia in Veterans With PTSD

    NCT05194930

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    1 US recruiting site
  23. Cereset Research for Caregivers

    NCT05209438

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  24. Insomnia Behavioral Intervention Study

    NCT05301543

    • Interventional
    • Ages 55 to 85 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  25. Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior

    NCT05390918

    • Interventional
    • Ages 11 to 18 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  26. The Effect of Sleep Loss on Emotion Regulation

    NCT05393830

    • Interventional
    • Ages 18 to 40 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  27. Pimavanserin for Insomnia in Veterans With PTSD

    NCT05441280

    • Phase 2
    • Ages 18 to 64 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  28. Forehead Temperature-Regulating Therapy for Insomnia in Adults With Tourette's Disorder

    NCT05499741

    • Interventional
    • Ages 18 to 50 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  29. Benefits of Nicotinamide Riboside Upon Cognition and Sleep

    NCT05500170

    • Interventional
    • Ages 65 to 85 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  30. Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder

    NCT05516277

    • Interventional
    • Ages 50 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site

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Insomnia clinical trials by city

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining an Insomnia clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.