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Benefits of Nicotinamide Riboside Upon Cognition and Sleep

NCT05500170

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Poor sleep quality and short sleep duration may be a mechanistic component of cognitive impairment in older adults, associated with a decline in brain-derived neurotrophic factor. Increasing the availability of nicotinamide adenine dinucleotide (NAD+) with supplementation of its precursor, nicotinamide riboside (NR), a form of vitamin B3 may increase the expression of brain-derived neurotrophic factor.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Cognitive Impairment
  • Sleep Quality

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
65 to 85 years
Sex
All
Healthy volunteers
Accepted
Sponsor
State University of New York at Buffalo
Last updated on ClinicalTrials.gov
September 24, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

New York · 1

  • Buffalo Veteran Affairs Medical Center · Buffalo, NY

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.