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Depression Clinical Trials near Durham, NC

21 studies for Depression are recruiting at 22 sites within 50 miles of Durham, North Carolina, according to ClinicalTrials.gov data processed .

Distances are city-level approximations. See all Depression trials in the US or all trials near Durham.

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Recruiting now

Depression studies enrolling near Durham

Showing 21 studies, nearest first.
  1. Supporting Health in Veterans With Heart Failure

    NCT05839067

    • Interventional
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: VA Clinic - Durham (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  2. A New Intervention to Improve Function in Veterans With Anxiety and Depression

    NCT06188923

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Durham VA Medical Center, Durham, NC (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  3. Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors

    NCT06538246

    • Interventional
    • Ages 18 years and older
    • Sex: All

    Nearest site: Duke University Medical Center (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  4. SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families

    NCT06627764

    • Interventional
    • Ages 12 to 100 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Duke School of Nursing (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  5. Allopregnanolone (Zuranolone) in Post-stroke Depression

    NCT06759558

    • Phase 2
    • Ages 21 to 65 years
    • Sex: All

    Nearest site: Duke South Neurology Clinic 1L (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  6. Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking

    NCT07050355

    • Interventional
    • Ages 21 years and older
    • Sex: All

    Nearest site: Duke University School of Medicine (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  7. Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Major Depressive Disorder

    NCT07282678

    • Interventional
    • Ages 22 years and older
    • Sex: All

    Nearest site: Qortical Clinical Partners (Durham, NC)

    Distance to nearest recruiting site
    <1 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  8. Examining the Effects of Estradiol on Neural and Molecular Response to Reward

    NCT05282277

    • Phase 4
    • Ages 45 to 55 years
    • Sex: Female

    Nearest site: University of North Carolina at Chapel Hill (Chapel Hill, NC)

    Distance to nearest recruiting site
    ~10 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  9. Adolescent Mood During Puberty and Testosterone

    NCT06072677

    • Interventional
    • Ages 11 to 14 years
    • Sex: All
    • Accepts healthy volunteers

    Nearest site: Carolina Crossing B, Suite 1 (Chapel Hill, NC)

    Distance to nearest recruiting site
    ~10 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  10. Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)

    NCT06587230

    • Interventional
    • Ages 5 to 99 years
    • Sex: All

    Nearest site: University of North Carolina at Chapel Hill (Chapel Hill, NC)

    Distance to nearest recruiting site
    ~10 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  11. Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression

    NCT06610305

    • Phase 4
    • Ages 18 to 45 years
    • Sex: Female

    Nearest site: University of North Carolina, Chapel Hill (Chapel Hill, NC)

    Distance to nearest recruiting site
    ~10 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  12. Neuroscience of Psychotherapy for Depression

    NCT06696001

    • Interventional
    • Ages 18 to 30 years
    • Sex: All

    Nearest site: Carolina Center for Neurostimulation (Chapel Hill, NC)

    Distance to nearest recruiting site
    ~10 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  13. RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

    NCT07002034

    • Phase 2
    • Ages 18 to 80 years
    • Sex: All

    Nearest site: University of North Carolina at Chapel Hill (Chapel Hill, NC)

    Distance to nearest recruiting site
    ~10 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  14. TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

    NCT07048574

    • Observational
    • Ages 18 months to 11 years
    • Sex: All

    Nearest site: University of North Carolina School of Medicine (Chapel Hill, NC)

    Distance to nearest recruiting site
    ~10 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  15. CARED : A Novel Rapid Treatment Paradigm for Depression

    NCT07507370

    • Interventional
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: Carolina Center for Neurostimulation (Chapel Hill, NC)

    Distance to nearest recruiting site
    ~10 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  16. Brexanolone Lifting Outcomes Of Moms

    NCT07822321

    • Phase 3
    • Ages 15 to 45 years
    • Sex: Female

    Nearest site: Lipocine Investigational Site (Chapel Hill, NC)

    Distance to nearest recruiting site
    ~10 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  17. ALTO-100 in Bipolar Disorder With Depression (BD-D)

    NCT06656416

    • Phase 2
    • Ages 18 to 70 years
    • Sex: All

    Nearest site: Site 6127 (Cary, NC)

    Distance to nearest recruiting site
    ~16 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  18. ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

    NCT07284667

    • Phase 2
    • Ages 18 to 65 years
    • Sex: All

    Nearest site: Magnolia Clinical Research, LLC (Cary, NC)

    Distance to nearest recruiting site
    ~16 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  19. A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder

    NCT07573176

    • Phase 3
    • Ages 18 to 74 years
    • Sex: All

    Nearest site: Magnolia Clinical Research LLC (Cary, NC)

    Distance to nearest recruiting site
    ~16 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  20. A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

    NCT07115329

    • Phase 2
    • Ages 18 to 64 years
    • Sex: All

    Nearest site: UNC Health Rex (Raleigh, NC)

    Distance to nearest recruiting site
    ~21 mi (city-level)
    Recruiting sites
    1 site within 50 mi
  21. E-Mindfulness Approaches for Living After Breast Cancer

    NCT06748222

    • Phase 3
    • Ages 18 to 50 years
    • Sex: All

    Nearest sites: Cone Health Cancer Center at Alamance Regional (Burlington, NC); Annie Penn Memorial Hospital (Reidsville, NC)

    Distance to nearest recruiting site
    ~31 mi (city-level)
    Recruiting sites
    2 sites within 50 mi

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Depression clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.