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Chronic Low Back Pain Clinical Trials Recruiting in the US

73 studies for Chronic Low Back Pain are recruiting at 195 US sites, according to ClinicalTrials.gov data processed .

Chronic low back pain is pain in the lower back that lasts for 12 weeks or longer.

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Recruiting now

Top Chronic Low Back Pain studies by number of US sites

Showing 30 studies, most US recruiting sites first.
  1. A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain

    NCT07641504

    • Phase 2
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    32 US recruiting sites
  2. A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease

    NCT07254806

    • Phase 3
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    30 US recruiting sites
  3. Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain

    NCT06827262

    • Observational
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    19 US recruiting sites
  4. Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response

    NCT04142177

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    13 US recruiting sites
  5. Examination of Nociscan Impact on Low Back Pain Surgical Outcomes

    NCT06661850

    • Observational
    • Ages 18 to 70 years
    • Sex: All
    Recruiting sites
    10 US recruiting sites
  6. Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control

    NCT07190807

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    7 US recruiting sites
  7. PerQdisc Traditional Feasibility Trial.

    NCT06860867

    • Interventional
    • Ages 22 to 70 years
    • Sex: All
    Recruiting sites
    5 US recruiting sites
  8. Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain

    NCT06361485

    • Phase 1
    • Ages 20 years and older
    • Sex: All
    Recruiting sites
    4 US recruiting sites
  9. Telerehabilitation for Patients With Chronic Low Back Pain (TeleBACK Clinical Trial)

    NCT06821607

    • Interventional
    • Ages 18 to 64 years
    • Sex: All
    Recruiting sites
    3 US recruiting sites
  10. Time to BBVNA Relief

    NCT07433634

    • Observational
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    3 US recruiting sites
  11. Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.

    NCT05721027

    • Phase 4
    • Ages 18 to 70 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    2 US recruiting sites
  12. Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery

    NCT06282770

    • Interventional
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    2 US recruiting sites
  13. Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P)

    NCT06671132

    • Phase 2
    • Ages 18 to 85 years
    • Sex: All
    Recruiting sites
    2 US recruiting sites
  14. Peripheral Nerve Stimulation With the SPRINT® System in Chronic PSIJC Pain

    NCT07166952

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    2 US recruiting sites
  15. A Superiority Trial of Radiofrequency Ablation for Low Back Pain

    NCT07222462

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    2 US recruiting sites
  16. A Multi-Site Feasibility Trial of Embedded Emergency Department Physical Therapy

    NCT07224945

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    2 US recruiting sites
  17. Evaluation of the Effects of a Rehabilitation Program in Individuals with Spine Pain

    NCT04081896

    • Observational
    • Ages 18 to 89 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  18. Feasibility of Identifying Brain Mechanisms of Qigong and Behavioral Outcomes After Qigong Practice in People With Chronic Low Back Pain

    NCT04164225

    • Interventional
    • Ages 18 to 70 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  19. The Effect of Yoga Practice on Chronic Back Pain

    NCT04270617

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    1 US recruiting site
  20. Trigger Point Injection for Myofascial Pain Syndrome in the Low Back: A Randomized Controlled Trial

    NCT04704297

    • Phase 4
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  21. PRECISION Pain Research Registry

    NCT04853732

    • Observational
    • Ages 21 to 79 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  22. Brain Mechanisms Supporting Cannabis-induced Pain Relief

    NCT04982965

    • Early Phase 1
    • Ages 21 to 65 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  23. Strain-Counterstrain Treatment of Piriformis Pain

    NCT05023005

    • Interventional
    • Ages 18 to 65 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  24. Therapeutic Mechanisms of Epidural Spinal Cord Stimulation

    NCT05556902

    • Interventional
    • Ages 18 to 89 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  25. Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain

    NCT05607381

    • Interventional
    • Ages 18 to 65 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  26. Randomized Trial for cLBP (Gokhale Project)

    NCT05657964

    • Observational
    • Ages 18 to 65 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  27. Mobile Neurofeedback for Low Back Pain

    NCT05669027

    • Interventional
    • Ages 18 to 90 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  28. Overlapping Pain Trajectory Study

    NCT05752396

    • Observational
    • Ages 10 to 19 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  29. The Spine Phenome Project

    NCT05776771

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  30. Tailored Pain Guide (TPG) Study

    NCT05843890

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    1 US recruiting site

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a Chronic Low Back Pain clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.