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Brain Mechanisms Supporting Cannabis-induced Pain Relief

NCT04982965

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Chronic low back pain is a common and disabling condition that affects millions of people in the United States. Many people with chronic low back pain do not get enough relief from current treatments. Cannabis may help reduce pain, but researchers do not fully understand how it affects the brain in people with chronic pain. The purpose of this study is to examine how inhaled cannabis changes brain activity and reduces pain in people with chronic low back pain.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Sciatica
  • Lumbar Radiculopathy
  • Lower Back Pain
  • Degenerative Disc Disease
  • Chronic Low-back Pain (cLBP)
  • Chronic Low Back and Leg Pain
  • Back Pain

Eligibility basics and study details

Study type
Interventional
Phase
Early Phase 1
Ages
21 to 65 years
Sex
All
Healthy volunteers
Accepted
Sponsor
University of California, San Diego
Last updated on ClinicalTrials.gov
June 3, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 1

  • Center for Functional MRI - W.M.Keck Building · La Jolla, CA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.