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UNderstanding the Causes Of Idiopathic Scoliosis Through the Longitudinal Analysis of Proteomic Markers: the UNCOIL Study

NCT07634627

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The goal of this observational study is to find clinical, demographic, and protein biomarkers that scoliosis progression (scoliosis curve increases) and/or differ between participants with scoliosis versus those without scoliosis. The investigators aim to answer the following questions: Are age, sex, skeletal maturity, and family history associated with scoliosis curve progression? Do protein levels differ between progressive and non-progressive cases? Do protein levels change between baseline and follow-up visits in progressive and non-progressive scoliosis cases?

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Adolescent Idiopathic Scoliosis (AIS)
  • Neuromuscular Scoliosis

Eligibility basics and study details

Study type
Observational
Phase
Not applicable
Ages
10 to 17 years
Sex
All
Healthy volunteers
Accepted
Sponsor
University of Colorado, Denver
Last updated on ClinicalTrials.gov
June 23, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Colorado · 1

  • Children's Hospital Colorado Anschutz · Aurora, CO

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.