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Evaluation of [11C]ZTP-1 to Image PDE4B

NCT07625345

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Background: PDE4B is a protein in cells that helps turn off certain chemical signals after they ve done their job. It controls inflammation, immune responses, and some brain signaling. Measuring PDE4B levels in the body can help doctors manage a disease or know if a treatment is working. Researchers want to find out if a new tracer (a radioactive substance injected during imaging scans) can help them measure PDE4B in people more effectively. Objective: To test a new tracer ([11C]ZTP-1) during imaging scans of the brain and body in healthy people. Eligibility: Healthy people aged 18 and older.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Healthy

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1
Ages
18 to 101 years
Sex
All
Healthy volunteers
Accepted
Sponsor
National Institute of Mental Health (NIMH)
Last updated on ClinicalTrials.gov
October 1, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Maryland · 1

  • National Institutes of Health Clinical Center · Bethesda, MD

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.