Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial
NCT07567040
This study is recruiting at 12 US sites in 10 states, according to its ClinicalTrials.gov record last updated .
Summary
The aims of this clinical trial will test whether or not the onset of nearsightedness is delayed in a group of children randomized to nightly drops in 0.05% atropine in both eyes, in comparison to children who receiving nightly placebo drops in both eyes. The primary outcome is the two-year cumulative incidence of nearsightedness. The second aim of this project will determine whether atropine is associated with slower eye growth in children receiving nightly drops of atropine versus placebo.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Myopia
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 6 to 11 years
- Sex
- All
- Healthy volunteers
- Accepted
- Sponsor
- Ohio State University
- Last updated on ClinicalTrials.gov
- September 21, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- University of Alabama School of Optometry · Birmingham, AL
California · 3
- University of California, Berkeley, School of Optometry · Berkeley, CA
- Southern California College of Optometry at Marshall B. Ketchum University · Fullerton, CA
- Stanford University · Palo Alto, CA
Illinois · 1
- Illinois College of Optometry · Chicago, IL
Indiana · 1
- Indiana University · Bloomington, IN
Massachusetts · 1
- New England College of Optometry · Boston, MA
New York · 1
- State University of New York College of Optometry · New York, NY
Ohio · 1
- The Ohio State University College of Optometry · Columbus, OH
Pennsylvania · 1
- Pennsylvania College of Optometry at Drexel University · Elkins Park, PA
Tennessee · 1
- Southern College of Optometry · Memphis, TN
Texas · 1
- University of Houston College of Optometry · Houston, TX
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.