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Psilocybin Administration With 5-HT1a Blockade

NCT07565493

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The purpose of this study is to assess the effects of 5-HT1A receptor blockade on the acute subjective effects of psilocybin, as measured through subjective survey measures and acute electroencephalography (EEG). Further, the investigators will assess the effects of psilocybin on post-acute sleep and dreaming through the use of sleep EEG and sleep and dream diaries.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Psychedelic Effects in Healthy Volunteers

Eligibility basics and study details

Study type
Interventional
Phase
Early Phase 1
Ages
21 to 60 years
Sex
All
Healthy volunteers
Accepted
Sponsor
Johns Hopkins University
Last updated on ClinicalTrials.gov
September 14, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Maryland · 1

  • Center for Psychedelics and Consciousness Research · Baltimore, MD

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.