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Estrogen to Improve Quality of Life for Men With Newly Diagnosed or Recurrent Metastatic Hormone Sensitive Prostate Cancer, EQUIP Trial

NCT07466498

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

This phase II trial compares giving estrogen with an androgen receptor signaling inhibitor to standard of care luteinizing hormone-releasing hormone (LHRH) analogues with an androgen receptor signaling inhibitor for improving quality of life for patients with hormone sensitive prostate cancer that is newly diagnosed or that has come back after a period of improvement (recurrent) and has spread from where it first started (primary site) to other places in the body (metastatic).

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Castration-Sensitive Prostate Adenocarcinoma
  • Metastatic Castration-Sensitive Prostate Adenocarcinoma
  • Stage IVB Prostate Cancer AJCC v8

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 years and older
Sex
Male
Healthy volunteers
Not accepted
Sponsor
Fred Hutchinson Cancer Center
Last updated on ClinicalTrials.gov
October 16, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Washington · 1

  • Fred Hutch/University of Washington Cancer Consortium · Seattle, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.