Hemophilia A Research Program

Summary

This study longitudinally observes the intergenerational (mother-child) continuum in hemophilia A from pregnancy through early childhood. Because the study follows mother-child pairs, the study includes both a maternal cohort and a pediatric cohort. Each cohort has a primary goal: for the mother with a severe hemophilia genotype, the overarching primary goal is to understand the risks for pregnancy-associated bleeding and postpartum hemorrhage (PPH); for the child, the overarching primary goal is to understand the risks, timing, and circumstances of development of anti-FVIII antibodies.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

• Hemophilia A
• Hemophilia A, Severe
• Factor VIII (FVIII)
• FVIII Deficiency
• Carrier of Hemophilia A
• Inhibitors
• Pregnancy
• Maternal Blood Loss
• Pregnancy Complications
• Bleeding Disorder
• Hemorrhage, Postpartum
• Alloimmunization
• X-Linked

Eligibility basics and study details

Study type

Observational

Phase

Not applicable

Ages

Any age

Sex

All

Healthy volunteers

Accepted

Sponsor

University of Washington

Last updated on ClinicalTrials.gov

February 17, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites