A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
NCT07351045
This study is recruiting at 44 US sites in 25 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon like peptide-1 (GLP-1)/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist (RA), at multiple doses compared with placebo for weight management in participants without Type 2 diabetes mellitus (T2DM) who have obesity or overweight with at least one weight-related comorbidity.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Obesity or Overweight
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Hoffmann-La Roche
- Last updated on ClinicalTrials.gov
- October 13, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 3
- Pinnacle Research Group · Anniston, AL
- Alabama Clinical Therapeutics · Birmingham, AL
- University of Alabama at Birmingham · Birmingham, AL
Arizona · 1
- Arizona Clinical Trials · Tucson, AZ
California · 3
- University of California Irvine · Irvine, CA
- Artemis Institute for Clinical Research, LLC · San Diego, CA
- Diablo Clinical Research, Inc. · Walnut Creek, CA
Connecticut · 1
- Yale University · New Haven, CT
Georgia · 1
- Rophe Adult and Pediatric Medicine/SKYCRNG · Union City, GA
Hawaii · 1
- East-West Medical Research Institute · Honolulu, HI
Illinois · 3
- Elevate Clinical Research · Gurnee, IL
- Knownwell · Schaumburg, IL
- Endeavor Health · Skokie, IL
Kentucky · 1
- Monroe Biomedical Research · Louisville, KY
Louisiana · 1
- Ascension DePaul Health · New Orleans, LA
Maryland · 2
- Baltimore VA Medical Center · Baltimore, MD
- Johns Hopkins University School of Nursing · Baltimore, MD
Massachusetts · 2
- Boston Medical Center · Boston, MA
- Knownwell · Needham, MA
Minnesota · 1
- International Diabetes Center At Park Nicollet · Minneapolis, MN
Mississippi · 1
- DelRicht Research at Gulfport Memorial · Gulfport, MS
Missouri · 1
- Clinvest Research LLC · Springfield, MO
New York · 1
- Rochester Clinical Research · Buffalo, NY
Ohio · 1
- Hometown Urgent Care and Research - Dayton · Dayton, OH
Oklahoma · 1
- Delricht Research of Tulsa Clinical Trials · Tulsa, OK
Oregon · 1
- Headlands Reseach- Summit · Portland, OR
Pennsylvania · 1
- Suburban Research Associates - West Chester Office · West Chester, PA
South Carolina · 1
- Trial Management Associates · Myrtle Beach, SC
South Dakota · 1
- Circle Clinical Research · Sioux Falls, SD
Tennessee · 2
- Innovative Clinical Research · Clarksville, TN
- Clinical Research Associates · Nashville, TN
Texas · 11
- Bellaire Clinical Research, LLC · Bellaire, TX
- South Texas Research Institute - Brownsville · Brownsville, TX
- South Texas Clinical Research · Corpus Christi, TX
- University of Texas Southwestern Medical Center - Children's Medical Center Dallas · Dallas, TX
- Elevate Clinical · Houston, TX
- Houston Research Institute · Houston, TX
- Elevate Clinical · McAllen, TX
- IMA Clinical Research - San Antonio · San Antonio, TX
- Pinnacle Clinical Research - South San Antonio · San Antonio, TX
- Consano Clinical Research · Shavano Park, TX
- Texas Digestive Disease Consultants, PLLC d/b/a GI Alliance · Southlake, TX
Utah · 1
- George E. Wahlen Department of Veterans Affairs Medical Center · Salt Lake City, UT
Wisconsin · 1
- Ascension Columbia St. Mary's · Milwaukee, WI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.