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Vancomycin in TKAs

NCT07282782

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Periprosthetic joint infection (PJI) is a national health crisis and leads to very poor outcomes for patients undergoing elective joint replacement. Within the realm of elective total knee arthroplasty (TKA), various methods of infection prophylaxis are in place. These include sterile precautions, would/tissue handling, and antibiotic prophylaxis. With respect to the latter, various approaches have been utilized including intravenous and intraosseous administration of vancomycin, preoperatively. Intraosseous administration does require another wound and a specific device to administer.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Total Knee Arthroplasty

Eligibility basics and study details

Study type
Interventional
Phase
Phase 4
Ages
18 years and older
Sex
All
Healthy volunteers
Accepted
Sponsor
University of California, San Diego
Last updated on ClinicalTrials.gov
June 3, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 1

  • University of California, San Diego · San Diego, CA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.