A Study to Learn How the Body Processes the Study Medicine Called Vepdegestrant in People With Loss of Liver Function

Summary

The purpose of the study is to look at how the body processes a study medicine called vepdegestrant in participants with loss of liver function relative to people with normal liver function. This study is seeking participants who are: females who cannot have children or males between 18 and 70 years of age weigh more than 50 Kilograms (110 pounds) either healthy with normal liver function or have loss of liver function All participants in this study will take one dose of vepdegestrant by mouth.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

• Healthy Participants

Eligibility basics and study details

Study type

Interventional

Phase

Phase 1

Ages

18 to 70 years

Sex

All

Healthy volunteers

Accepted

Sponsor

Pfizer

Last updated on ClinicalTrials.gov

April 3, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites