Timing of Opioid Administration and Postoperative Respiratory Depression.

Summary

The goal of this study is to determine if a relationship can be detected between the administration of an opioid and quantitative respiratory depression in spontaneously breathing non-intubated patients who have undergone general anesthesia and have received perioperative opioids. The primary aim is to determine the temporal effect of opioid administration on respiratory depression as assessed by minute ventilation with a reduction of at least 20% in the percent of predicted minute ventilation.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

• Respiratory Complications
• Opioid Induced Respiratory Depression
• Postoperative Respiratory Complications

Eligibility basics and study details

Study type

Observational

Phase

Not applicable

Ages

18 to 85 years

Sex

All

Healthy volunteers

Accepted

Sponsor

Wayne State University

Last updated on ClinicalTrials.gov

July 16, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites