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PRoMiSS: Psilocybin and the Role of Music in Set and Setting

NCT07180108

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The goal of this clinical trial is to understand how personally meaningful, autobiographically salient music compares to standardized playlists when combined with psilocybin in healthy adults ages 21 to 75. The main questions it aims to answer are: Does autobiographically salient music lead to stronger emotional responses to music, greater acute subjective effects, and more lasting improvements in mood, affect, and well-being compared to standardized or ambient playlists?

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Psilocybin
  • Music Intervention

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1
Ages
21 to 75 years
Sex
All
Healthy volunteers
Accepted
Sponsor
Johns Hopkins University
Last updated on ClinicalTrials.gov
September 15, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Maryland · 1

  • Center for Psychedelics and Consciousness Research in the Behavioral Biology Research Center · Baltimore, MD

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.