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Characterizing the Human Airway Immune Response to FluMist Vaccination

NCT07177417

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The goal of this clinical trial is to measure the immune response in the blood, nose, and lungs after participants receive either the FDA-approved inactivated influenza vaccine or the FDA-approved intranasal FluMist vaccine. The study will evaluate immune responses in groups of healthy, non-pregnant, volunteers between the ages of 18 and 40. The main purpose of the study is to measure the change in influenza vaccine-specific antibodies in the lower lungs and nose between vaccination and 14 days after participants receive the vaccine.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Healthy Young Adults
  • Influenza Vaccines
  • Influenza Vaccine Response

Eligibility basics and study details

Study type
Interventional
Phase
Phase 4
Ages
18 to 40 years
Sex
All
Healthy volunteers
Accepted
Sponsor
Washington University School of Medicine
Last updated on ClinicalTrials.gov
September 17, 2025

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Missouri · 1

  • Washington University in Saint Louis School of Medicine Emergency Care and Research Core · St Louis, MO

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.